Objective. Gastrointestinal symptoms that occur without evidence of structural gastrointestinal disease are a well- recognized feature of patients with eating disorders (EDs). Despite this, the spectrum and predictors...Objective. Gastrointestinal symptoms that occur without evidence of structural gastrointestinal disease are a well- recognized feature of patients with eating disorders (EDs). Despite this, the spectrum and predictors of specific functional gastrointestinal disorders (FGIDs), documented using standardized and validated questionnaires, have received little attention. The aims of the study were to describe the prevalence and type of FGIDs in patients suffering from anorexia nervosa (AN), bulimia nervosa (BN) and eating disorders not otherwise specified (EDNOS), and to determine the relationships between psychological features, eating- disordered attitudes and behaviours, demographic characteristics and the type and number of FGIDs present. Material and methods. A total of 101 consecutive female patients admitted to an eating disorder unit (AN 44% , BN 22% , EDNOS 34% , mean age 21 years) completed the Rome II modular questionnaire and a range of other validated self- reported questionnaires detailing illness history, psychological features and eating and exercise behaviour. Results. The criteria for at least one FGID were fulfilled by 98% of the sample. The most prevalent FGIDs were irritable bowel syndrome (IBS: 52% ), functional heartburn (FH: 51% ), functional abdominal bloating (31% ), functional constipation (FC: 24% ), functional dysphagia (23% ) and functional anorectal pain disorder (FAno: 22% ); 52% of the sample satisfied the criteria for at least three coexistent FGIDs. Psychological variables (somatization, neuroticism, state and trait anxiety), age and binge eating were significant predictors of specific, and ≥ 3 coexistent FGIDs. Other disordered eating characteristics, including body mass index, were not predictors. Conclusions. In patients with EDs, specific psychological traits predict FGID type and the presence of multiple coexistent FGIDs. These findings support the role of specific psychological features as important contributors to certain FGIDs.展开更多
Background: Focal outbreaks of sexually transmitted infections (STIs) such as syphilis and gonorrhoea have been reported in the large cities of Western Europe over the past few years. The aim of our study was to deter...Background: Focal outbreaks of sexually transmitted infections (STIs) such as syphilis and gonorrhoea have been reported in the large cities of Western Europe over the past few years. The aim of our study was to determine whether a similar trend is observed in Geneva and the situation with regard to HIV infection. Methods: We review the incidence of syphilis, gonorrhoea, Chlamydia trachomatis and HIV in Geneva from 1999 to 2004. Results: Figures indicate a steady and sustained increase in the incidence of syphilis, gonorrhoea and Chlamydia trachomatis in Geneva since 1999 that is maintained into 2004. As for HIV, the number of positive testings in Switzerland has stabilised and primary infection figures do not indicate an increase in newly acquired infections in Geneva. Conclusion: The situation in Geneva is similar to that observed elsewhere inWestern Europe and indicates the need of public health interventions.展开更多
We report the case of a human immunodeficiency virus-positive patient presenting linear Darier disease with varicella-zoster virus superinfection following the lines of Blaschko. The lesions healed after treatment wit...We report the case of a human immunodeficiency virus-positive patient presenting linear Darier disease with varicella-zoster virus superinfection following the lines of Blaschko. The lesions healed after treatment with brivudine.展开更多
文摘Objective. Gastrointestinal symptoms that occur without evidence of structural gastrointestinal disease are a well- recognized feature of patients with eating disorders (EDs). Despite this, the spectrum and predictors of specific functional gastrointestinal disorders (FGIDs), documented using standardized and validated questionnaires, have received little attention. The aims of the study were to describe the prevalence and type of FGIDs in patients suffering from anorexia nervosa (AN), bulimia nervosa (BN) and eating disorders not otherwise specified (EDNOS), and to determine the relationships between psychological features, eating- disordered attitudes and behaviours, demographic characteristics and the type and number of FGIDs present. Material and methods. A total of 101 consecutive female patients admitted to an eating disorder unit (AN 44% , BN 22% , EDNOS 34% , mean age 21 years) completed the Rome II modular questionnaire and a range of other validated self- reported questionnaires detailing illness history, psychological features and eating and exercise behaviour. Results. The criteria for at least one FGID were fulfilled by 98% of the sample. The most prevalent FGIDs were irritable bowel syndrome (IBS: 52% ), functional heartburn (FH: 51% ), functional abdominal bloating (31% ), functional constipation (FC: 24% ), functional dysphagia (23% ) and functional anorectal pain disorder (FAno: 22% ); 52% of the sample satisfied the criteria for at least three coexistent FGIDs. Psychological variables (somatization, neuroticism, state and trait anxiety), age and binge eating were significant predictors of specific, and ≥ 3 coexistent FGIDs. Other disordered eating characteristics, including body mass index, were not predictors. Conclusions. In patients with EDs, specific psychological traits predict FGID type and the presence of multiple coexistent FGIDs. These findings support the role of specific psychological features as important contributors to certain FGIDs.
文摘Background: Focal outbreaks of sexually transmitted infections (STIs) such as syphilis and gonorrhoea have been reported in the large cities of Western Europe over the past few years. The aim of our study was to determine whether a similar trend is observed in Geneva and the situation with regard to HIV infection. Methods: We review the incidence of syphilis, gonorrhoea, Chlamydia trachomatis and HIV in Geneva from 1999 to 2004. Results: Figures indicate a steady and sustained increase in the incidence of syphilis, gonorrhoea and Chlamydia trachomatis in Geneva since 1999 that is maintained into 2004. As for HIV, the number of positive testings in Switzerland has stabilised and primary infection figures do not indicate an increase in newly acquired infections in Geneva. Conclusion: The situation in Geneva is similar to that observed elsewhere inWestern Europe and indicates the need of public health interventions.
文摘We report the case of a human immunodeficiency virus-positive patient presenting linear Darier disease with varicella-zoster virus superinfection following the lines of Blaschko. The lesions healed after treatment with brivudine.
