Leptin is one of the best known hormone markers for obesity. There is a limited anthropometric data in the Gaza Strip that reveals and arouses the nutritional status among all age groups especially adolescents aged 15...Leptin is one of the best known hormone markers for obesity. There is a limited anthropometric data in the Gaza Strip that reveals and arouses the nutritional status among all age groups especially adolescents aged 15 - 19 years old. The study aimed to assess the effect of Leptin hormone, lipid profiles, Body Mass Index (BMI) and waist circumference among secondary school age students in the Gaza Strip. Methodology: A cross sectional study included 442 cases of teenagers aged 15 - 19 years old from governmental and private schools in the Gaza strip. Blood samples were collected for analysis of Leptin hormone and lipid profile and measuring waist circumference for the teenager. Results: The mean of serum Leptin was (28.7) higher among cases than controls (28.1), but it was statistically insignificant (P = 0.85). It was found that there is a significant correlation between Leptin hormone and total cholesterol (Chol) (r = 0.24), high density cholesterol (HDL) (r = 0.27) and low density cholesterol (LDL) (r = 0.16). There was no relationship between Leptin hormone and triglycerides (TG) (r = -0.02). There was relationship between Leptin hormone and waist circumference in both males and females (r = 0.519, 0.544), respectively. There was no statistical significant deference noticed between Leptin hormone of obese objects and Leptin hormone of normal BMI objects of the same age (t-test = 0.93, P = 0.85). Conclusion: There are significant correlations between Leptin hormone and total Chol, HDL and LDL except for TG, and there were significant relationships between Leptin hormone and waist circumference which reflect the central obesity among males and females. There is no association between Leptin level and BMI.展开更多
Background: Overweight and obesity are among the most frequently encountered multi-factorial disorders in most populations of the world. In addition, to its health impacts, overweight/obesity leads to many health prob...Background: Overweight and obesity are among the most frequently encountered multi-factorial disorders in most populations of the world. In addition, to its health impacts, overweight/obesity leads to many health problems which reflect on the university students’ physical, psychological, social and environmental aspects of their quality of life. The study aim was to evaluate the effect of an educational program on improving quality of life of overweight/obese university students in Gaza strip. Materials and Methods: quasi-experimental nonequivalent pretest-posttest control group design utilized in this study 74 and 69 students in the intervention and control group respectively. The study conducted at Islamic university of Gaza and data were collected in two stages before and after five months from the application of the educational program, using interviewing questionnaire and world health organization quality of life-BREF instrument;pre-post test and body mass index were calculated. Results: the study results revealed that overall students’ knowledge for posttest was significantly higher than pretest (p-value ≤ 0.05). Overall, mean score of quality of life after the program was significantly (p-value = 0.001) greater than before and greater than control group for all domains. Conclusion: The study concluded that the health educational intervention program had positive effects on knowledge, practices and attitudes regarding overweight/obesity with improving university students’ mean score of quality of life.展开更多
Statins, which are inhibitors of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, are considered as one of the most important drugs and the drug of choice for reducing an abnormal cholesterol level. Statins are nor...Statins, which are inhibitors of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, are considered as one of the most important drugs and the drug of choice for reducing an abnormal cholesterol level. Statins are normally used to decrease the risk of coronary heart disease (CHD), but they tend to be associated with liver adverse effects. The objective of this prospective study was to investigate the effect of atorvastatin therapy on the liver function in patients with CHD. Study comprised of 66 newly diagnosed CHD patients who were selected from UNRWA clinics in the Gaza Strip. The patients were clinically examined and treated with atorvastatin (10 - 40 mg/day). A questionnaire was used to collect the data concerning patient’s characteristics. Total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), liver enzymes tests such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and total and direct blood bilirubin were measured before starting treatment and after 3 and 6 months of treatment. The results showed a significant increase in the mean values of ALT, AST, total bilirubin and direct bilirubin levels after 3 months then decreased after the next 3 months, but they were higher than the baseline with insignificant association.展开更多
文摘Leptin is one of the best known hormone markers for obesity. There is a limited anthropometric data in the Gaza Strip that reveals and arouses the nutritional status among all age groups especially adolescents aged 15 - 19 years old. The study aimed to assess the effect of Leptin hormone, lipid profiles, Body Mass Index (BMI) and waist circumference among secondary school age students in the Gaza Strip. Methodology: A cross sectional study included 442 cases of teenagers aged 15 - 19 years old from governmental and private schools in the Gaza strip. Blood samples were collected for analysis of Leptin hormone and lipid profile and measuring waist circumference for the teenager. Results: The mean of serum Leptin was (28.7) higher among cases than controls (28.1), but it was statistically insignificant (P = 0.85). It was found that there is a significant correlation between Leptin hormone and total cholesterol (Chol) (r = 0.24), high density cholesterol (HDL) (r = 0.27) and low density cholesterol (LDL) (r = 0.16). There was no relationship between Leptin hormone and triglycerides (TG) (r = -0.02). There was relationship between Leptin hormone and waist circumference in both males and females (r = 0.519, 0.544), respectively. There was no statistical significant deference noticed between Leptin hormone of obese objects and Leptin hormone of normal BMI objects of the same age (t-test = 0.93, P = 0.85). Conclusion: There are significant correlations between Leptin hormone and total Chol, HDL and LDL except for TG, and there were significant relationships between Leptin hormone and waist circumference which reflect the central obesity among males and females. There is no association between Leptin level and BMI.
文摘Background: Overweight and obesity are among the most frequently encountered multi-factorial disorders in most populations of the world. In addition, to its health impacts, overweight/obesity leads to many health problems which reflect on the university students’ physical, psychological, social and environmental aspects of their quality of life. The study aim was to evaluate the effect of an educational program on improving quality of life of overweight/obese university students in Gaza strip. Materials and Methods: quasi-experimental nonequivalent pretest-posttest control group design utilized in this study 74 and 69 students in the intervention and control group respectively. The study conducted at Islamic university of Gaza and data were collected in two stages before and after five months from the application of the educational program, using interviewing questionnaire and world health organization quality of life-BREF instrument;pre-post test and body mass index were calculated. Results: the study results revealed that overall students’ knowledge for posttest was significantly higher than pretest (p-value ≤ 0.05). Overall, mean score of quality of life after the program was significantly (p-value = 0.001) greater than before and greater than control group for all domains. Conclusion: The study concluded that the health educational intervention program had positive effects on knowledge, practices and attitudes regarding overweight/obesity with improving university students’ mean score of quality of life.
文摘Statins, which are inhibitors of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, are considered as one of the most important drugs and the drug of choice for reducing an abnormal cholesterol level. Statins are normally used to decrease the risk of coronary heart disease (CHD), but they tend to be associated with liver adverse effects. The objective of this prospective study was to investigate the effect of atorvastatin therapy on the liver function in patients with CHD. Study comprised of 66 newly diagnosed CHD patients who were selected from UNRWA clinics in the Gaza Strip. The patients were clinically examined and treated with atorvastatin (10 - 40 mg/day). A questionnaire was used to collect the data concerning patient’s characteristics. Total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), liver enzymes tests such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and total and direct blood bilirubin were measured before starting treatment and after 3 and 6 months of treatment. The results showed a significant increase in the mean values of ALT, AST, total bilirubin and direct bilirubin levels after 3 months then decreased after the next 3 months, but they were higher than the baseline with insignificant association.