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深度学习在冠状动脉内光学相干断层成像的研究进展
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作者 哈力木拉提·买买提 艾克力亚尔·艾尼瓦尔 +3 位作者 凯赛尔江·卡地尔 刘鹏飞 秦练 马翔 《中国介入心脏病学杂志》 CSCD 2024年第3期154-158,共5页
如今,冠心病仍然是影响人们生活质量和导致死亡的主要原因,因此冠状动脉病变的检测及治疗至关重要。光学相干断层成像是冠状动脉内斑块组织的鉴别方法。但由于医师的临床经验差异性,导致在诊断中产生分歧使患者无法得到精准治疗。深度... 如今,冠心病仍然是影响人们生活质量和导致死亡的主要原因,因此冠状动脉病变的检测及治疗至关重要。光学相干断层成像是冠状动脉内斑块组织的鉴别方法。但由于医师的临床经验差异性,导致在诊断中产生分歧使患者无法得到精准治疗。深度学习作为最先进的算法,能够自动提取深层特征,提高其在影像学诊断中的准确性和可靠性。本文将以深度学习在光学相干断层成像的应用进行综述,并对其在冠心病诊断中的未来前景进行展望。 展开更多
关键词 深度学习 冠心病 血管内光学相干断层成像
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深度学习在冠心病影像学诊断的研究进展 被引量:1
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作者 凯赛尔江·卡地尔 艾克力亚尔·艾尼瓦尔 +2 位作者 秦练 热娜·热合木丁 马翔 《心血管病学进展》 CAS 2022年第4期335-340,共6页
在心血管领域,医学影像与人工智能融合能深入挖掘影像数据特征,并且辅助疾病的诊断。冠心病的诊断主要依靠影像学检查,由于医生之间资历、水平的不同,个体主观原因产生的误差让诊断结果的准确性有所降低,处理数量庞大的影像数据也耗费... 在心血管领域,医学影像与人工智能融合能深入挖掘影像数据特征,并且辅助疾病的诊断。冠心病的诊断主要依靠影像学检查,由于医生之间资历、水平的不同,个体主观原因产生的误差让诊断结果的准确性有所降低,处理数量庞大的影像数据也耗费着医生大量的时间和精力。目前,深度学习作为人工智能的重要分支,在图像数据的处理上发挥着独特的优势,应用于冠心病影像诊断可提高诊断效率和准确性。现就深度学习技术在冠心病影像学诊断中的应用进行综述。 展开更多
关键词 深度学习 冠心病 医学影像 辅助诊断
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Correlation between betatrophin/angiogenin-likeprotein3/lipoprotein lipase pathway and severity of coronary artery disease in Kazakh patients with coronary heart disease 被引量:1
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作者 Lian Qin Rena Rehemuding +1 位作者 aikeliyaer ainiwaer Xiang Ma 《World Journal of Clinical Cases》 SCIE 2022年第7期2095-2105,共11页
BACKGROUND The results of previous animal experiments and clinical studies have shown that there is a correlation between expression of betatrophin and blood lipid levels.However,there are still differences studies on... BACKGROUND The results of previous animal experiments and clinical studies have shown that there is a correlation between expression of betatrophin and blood lipid levels.However,there are still differences studies on the correlation and interaction mechanism between betatrophin,angiogenin-likeprotein3(ANGPTL3)and lipoprotein lipase(LPL).In our previous studies,we found an increase in serum ANGPTL3 Levels in Chinese patients with coronary heart disease(CHD).Therefore,we retrospectively studied Kazakh CHD patients.AIM To explore the correlation between the betatrophin/ANGPTL3/LPL pathway and severity of coronary artery disease(CAD)in patients with CHD.METHODS Nondiabetic patients diagnosed with CHD were selected as the case group;79 were of Kazakh descent and 72 were of Han descent.The control groups comprised of 61 Kazakh and 65 Han individuals.The serum levels of betatrophin and LPL were detected by enzyme-linked immunosorbent assay(ELISA),and the double antibody sandwich ELISA was used to detect serum level of ANGPTL3.The levels of triglycerides,total cholesterol,and fasting blood glucose in each group were determined by an automatic biochemical analyzer.At the same time,the clinical baseline data of patients in each group were included.RESULTS Betatrophin,ANGPTL3 and LPL levels of Kazakh patients were significantly higher than those of Han patients(P=0.031,0.038,0.021 respectively).There was a positive correlation between the Gensini score and total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),betatrophin,and LPL in Kazakh patients(r=0.204,0.453,0.352,0.471,and 0.382 respectively),(P=0.043,0.009,0.048,0.001,and P<0.001 respectively).A positive correlation was found between the Gensini score and body mass index(BMI),TC,TG,LDL-C,LPL,betatrophin in Han patients(r=0.438,0.195,0.296,0.357,0.328,and 0.446 respectively),(P=0.044,0.026,0.003,0.20,0.004,and P<0.001).TG and betatrophin were the risk factors of coronary artery disease in Kazakh patients,while BMI and betatrophin were the risk factors in Han patients.CONCLUSION There was a correlation between the betatrophin/ANGPTL3/LPL pathway and severity of CAD in patients with CHD. 展开更多
关键词 Betatrophin/angiogenin-likeprotein3/Lipoprotein lipase pathway Coronary heart disease Gensini integral Coronary artery disease
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