[Objectives] The aim was to study chemical components of cultivated and wild Pinellia ternate(Thunb.) Breit and Typhonium flagelliforme(Lodd.) Blume by metabolomics technology based on UPLC-ESI-HRMS^n. [Methods] Chemi...[Objectives] The aim was to study chemical components of cultivated and wild Pinellia ternate(Thunb.) Breit and Typhonium flagelliforme(Lodd.) Blume by metabolomics technology based on UPLC-ESI-HRMS^n. [Methods] Chemical components of 27 samples of cultivated and wild P. ternate and T. flagelliforme were detected by using UPLC-ESI-HRMS^ntechnology. Differential markers between P. ternate and T. flagelliforme as well as cultivated and wild P. ternate were screened and identified by principal component analysis(PCA) and orthogonal partial least square-discriminate analysis(OPLS-DA). [Results]12 components of P. ternate(cultivated and wild variety) and T.flagelliforme and three components of cultivated and wild P. ternate were screened and identified by OPLS-DA. N-Acetyl-6-hydroxy-L-tryptophan and N-Phenylacetylglutamic were not detected in P. ternate,and these two components can be used as potential markers of P. ternate and T. flagelliforme. [Conclusions]UPLC-ESI-HRMS^n-based metabolomics technology could be used to quickly identify the chemical constituents of P. ternate and effectively distinguish P. ternate and T. flagelliforme,which has reference significance for the quality control of P. ternate.展开更多
This paper introduce the advances in study of antibacterial effects of natural medicines in the past ten years.The antibacterial components of natural medicines mainly include flavonoids,terpenoids,alkaloids,lignans,p...This paper introduce the advances in study of antibacterial effects of natural medicines in the past ten years.The antibacterial components of natural medicines mainly include flavonoids,terpenoids,alkaloids,lignans,phenols,etc..This paper is intended to provide data reference for the research and development of new natural antibacterial medicines.展开更多
基金Supported by Preferred Funding Plan of Science and Technology Activities Project for Overseas Students in Sichuan Province(2018-68)Key Project for Central Universities of Southwest Minzu University in 2018(2018NZD18)+1 种基金Research Project of Sichuan Province(2019YFS0174,2019YFS0191,2018JY0069)Innovative Scientific Research Project for Postgraduates of Southwest Minzu University(CX2017SZ092)
文摘[Objectives] The aim was to study chemical components of cultivated and wild Pinellia ternate(Thunb.) Breit and Typhonium flagelliforme(Lodd.) Blume by metabolomics technology based on UPLC-ESI-HRMS^n. [Methods] Chemical components of 27 samples of cultivated and wild P. ternate and T. flagelliforme were detected by using UPLC-ESI-HRMS^ntechnology. Differential markers between P. ternate and T. flagelliforme as well as cultivated and wild P. ternate were screened and identified by principal component analysis(PCA) and orthogonal partial least square-discriminate analysis(OPLS-DA). [Results]12 components of P. ternate(cultivated and wild variety) and T.flagelliforme and three components of cultivated and wild P. ternate were screened and identified by OPLS-DA. N-Acetyl-6-hydroxy-L-tryptophan and N-Phenylacetylglutamic were not detected in P. ternate,and these two components can be used as potential markers of P. ternate and T. flagelliforme. [Conclusions]UPLC-ESI-HRMS^n-based metabolomics technology could be used to quickly identify the chemical constituents of P. ternate and effectively distinguish P. ternate and T. flagelliforme,which has reference significance for the quality control of P. ternate.
基金National Key Research and Development Program of China(2017YFC1700705)Sichuan Provincial Scholars for Science and Technology Activities for Overseas Researchers(2018-68)+1 种基金Research Project of Sichuan Province(2019YFS0191)Innovating Research Program of Postgraduates of Southwest Minzu University(CX2018SZ86).
文摘This paper introduce the advances in study of antibacterial effects of natural medicines in the past ten years.The antibacterial components of natural medicines mainly include flavonoids,terpenoids,alkaloids,lignans,phenols,etc..This paper is intended to provide data reference for the research and development of new natural antibacterial medicines.
