Traditional designs and developments of bone biomaterials mostly concentrate on the positive regulation of osteoblast lineage cells,but often ignore the importance of immune responses and the equilibrium between bone ...Traditional designs and developments of bone biomaterials mostly concentrate on the positive regulation of osteoblast lineage cells,but often ignore the importance of immune responses and the equilibrium between bone resorption mediated by osteoclasts and bone formation mediated by osteoblasts.Immune dysregulation is associated with an imbalance between pro-inflammatory and anti-inflammatory processes,which may influence the efficacy of bone therapy.Therefore,implanted biomaterials should appropriately and precisely modulate subsequent immune responses.Magnesium(Mg)has been used to fabricate various Mg alloys for bone repair because of its favorable attributes such as osteogenic potential,immune regulation characteristics,biodegradability,and biocompatibility.Various basic research and clinical trials have been already conducted in many countries to explore the physical properties of Mg-containing implants and their clinical outcomes in bone fracture and defect repair.Therefore,this review summarizes the immune response to Mg-containing implants,and further organizes the current research and development progress of Mg-containing implants.The review aims to offer an overview of the current knowledge on immunomodulation of Mg-containing implants and future challenges in their clinical application,which could provide further insight in the development of better strategies for the treatment of bone defect and fracture.展开更多
[Objectives] This study was conducted to screen out pesticides that are highly effective against Tetranychus truncatus Ehara. [Methods] Nine kinds of pesticides were used to control pests on soybean. A petri dish effi...[Objectives] This study was conducted to screen out pesticides that are highly effective against Tetranychus truncatus Ehara. [Methods] Nine kinds of pesticides were used to control pests on soybean. A petri dish efficacy test was first performed in laboratory,then a leaf efficacy test was performed in a greenhouse,and finally,three kinds of agents with good efficacy in the two tests were selected for field control tests. [Results] The indoor and outdoor test results showed that abamectin was the best agent,which showed efficacy higher than 96%,followed by bifenthrin,whose efficacy was higher than 93%. It can be seen that abamectin is the best choice for the prevention and control of T. truncatus,and bifenthrin can also be used according to the situation. [Conclusions] This study provides a theoretical basis for the control of T. truncatus.展开更多
基金funded by Project of Liaoning Xingliao Talents Plan(XLYC2002103)Basic applied research program of Living Province of China(No.202220347-JH2/1013).
文摘Traditional designs and developments of bone biomaterials mostly concentrate on the positive regulation of osteoblast lineage cells,but often ignore the importance of immune responses and the equilibrium between bone resorption mediated by osteoclasts and bone formation mediated by osteoblasts.Immune dysregulation is associated with an imbalance between pro-inflammatory and anti-inflammatory processes,which may influence the efficacy of bone therapy.Therefore,implanted biomaterials should appropriately and precisely modulate subsequent immune responses.Magnesium(Mg)has been used to fabricate various Mg alloys for bone repair because of its favorable attributes such as osteogenic potential,immune regulation characteristics,biodegradability,and biocompatibility.Various basic research and clinical trials have been already conducted in many countries to explore the physical properties of Mg-containing implants and their clinical outcomes in bone fracture and defect repair.Therefore,this review summarizes the immune response to Mg-containing implants,and further organizes the current research and development progress of Mg-containing implants.The review aims to offer an overview of the current knowledge on immunomodulation of Mg-containing implants and future challenges in their clinical application,which could provide further insight in the development of better strategies for the treatment of bone defect and fracture.
基金Supported by the Cooperative Project Between the People's Republic of China and the Republic of Korea (413090094)。
文摘[Objectives] This study was conducted to screen out pesticides that are highly effective against Tetranychus truncatus Ehara. [Methods] Nine kinds of pesticides were used to control pests on soybean. A petri dish efficacy test was first performed in laboratory,then a leaf efficacy test was performed in a greenhouse,and finally,three kinds of agents with good efficacy in the two tests were selected for field control tests. [Results] The indoor and outdoor test results showed that abamectin was the best agent,which showed efficacy higher than 96%,followed by bifenthrin,whose efficacy was higher than 93%. It can be seen that abamectin is the best choice for the prevention and control of T. truncatus,and bifenthrin can also be used according to the situation. [Conclusions] This study provides a theoretical basis for the control of T. truncatus.
