dAIMTo evaluate the diagnostic value of dobutamine stress echocardiography （DSE） and myocardial perfusion sci-ntigraphy （MPS） in predicting coronary artery disease （CAD） in cirrhotic patients listed for liver tr...dAIMTo evaluate the diagnostic value of dobutamine stress echocardiography （DSE） and myocardial perfusion sci-ntigraphy （MPS） in predicting coronary artery disease （CAD） in cirrhotic patients listed for liver transplanta-tion （LT）, using invasive coronary angiography （ICA） as gold-standard.METHODSRetrieval of studies was based on Medical Subject Headings and Health Sciences Descriptors, which were combined using Boolean operators. Searches were run on the electronic databases Scopus, Web of Science, EMBASE, MEDLINE （PubMed）, BIREME （Biblioteca Regional de Medicina）, LILACS （Latin American and Cari-bbean Health Sciences Literature）, Cochrane Library for Systematic Reviews and Opengray.eu. There was reference lists of the studies retrieved were searched manually.RESULTSThe search strategy retrieved 322 references for DSE and 90 for MPS. In the fnal analysis, 10 references for DSE and 10 for MPS were included. Pooled sensitivity was 28% and 61% for DSE and MPS and specificity was 82% and 74%, for diagnosis of CAD using ICA as gold-standard, respectively.CONCLUSIONDSE and MPS do not have adequate sensitivity for determination of whether CAD is present, despite having signifcant specifcity.展开更多
文摘dAIMTo evaluate the diagnostic value of dobutamine stress echocardiography （DSE） and myocardial perfusion sci-ntigraphy （MPS） in predicting coronary artery disease （CAD） in cirrhotic patients listed for liver transplanta-tion （LT）, using invasive coronary angiography （ICA） as gold-standard.METHODSRetrieval of studies was based on Medical Subject Headings and Health Sciences Descriptors, which were combined using Boolean operators. Searches were run on the electronic databases Scopus, Web of Science, EMBASE, MEDLINE （PubMed）, BIREME （Biblioteca Regional de Medicina）, LILACS （Latin American and Cari-bbean Health Sciences Literature）, Cochrane Library for Systematic Reviews and Opengray.eu. There was reference lists of the studies retrieved were searched manually.RESULTSThe search strategy retrieved 322 references for DSE and 90 for MPS. In the fnal analysis, 10 references for DSE and 10 for MPS were included. Pooled sensitivity was 28% and 61% for DSE and MPS and specificity was 82% and 74%, for diagnosis of CAD using ICA as gold-standard, respectively.CONCLUSIONDSE and MPS do not have adequate sensitivity for determination of whether CAD is present, despite having signifcant specifcity.
