The ability of an organism to handle the beauty and cruelty of existence is largely due to a complex network of molecular and cellular interactions and processes named the immune system.Important components of this ne...The ability of an organism to handle the beauty and cruelty of existence is largely due to a complex network of molecular and cellular interactions and processes named the immune system.Important components of this network are antibodies(Abs)that have key roles in immune defense and regulation.Typical biological functions of Abs include neutralizing pathogens by blocking functionally important molecules and/or to eliciting lethal effector functions by bridging the recognition of pathogens with binding to different innate immune receptors.展开更多
基金This work was supported by Institut National de la Santéet de la Recherche Médicale(INSERM,France).A.R.R.is the recipient of a fellowship from an Innovative Training Network(ITN)funded by the European Union’s Horizon 2020 Program under grant agreement No 859974,project EDUC8.
文摘The ability of an organism to handle the beauty and cruelty of existence is largely due to a complex network of molecular and cellular interactions and processes named the immune system.Important components of this network are antibodies(Abs)that have key roles in immune defense and regulation.Typical biological functions of Abs include neutralizing pathogens by blocking functionally important molecules and/or to eliciting lethal effector functions by bridging the recognition of pathogens with binding to different innate immune receptors.