We were very pleased by the paper of Borrelli and colleagues(1)and we would thank for their consideration.Nowadays,macular diseases,such as age-related macular degeneration(AMD)underwent a strong improvement in terms ...We were very pleased by the paper of Borrelli and colleagues(1)and we would thank for their consideration.Nowadays,macular diseases,such as age-related macular degeneration(AMD)underwent a strong improvement in terms of pathophysiology understanding and treatments efficacy monitoring,thank to multimodal imaging techniques.These methodologies are reliable,feasible,easily reproducible,and provide very detailed microstructural information regarding retinal status in a non invasively way.Their introduction in clinical practice opened new frontiers for the ophthalmologists to face macular diseases.One of the most recently introduced technique is optical coherence tomography angiography(OCTA),which offered for the first time the opportunity to study in detail the retinal vascular network without the adoption of dye.Although multimodal imaging is mainly analyzed from the qualitative point of view,in the last years even more advanced quantitative approaches were introduced to further improve the amount of information reached by images analyses.In the context of OCTA,vessel density still represents the most used measure;it provides useful information regarding vascular deficits occurring in macular diseases(2).However,vessel density reductions resulted not pathognomonic of given retinal diseases.展开更多
文摘We were very pleased by the paper of Borrelli and colleagues(1)and we would thank for their consideration.Nowadays,macular diseases,such as age-related macular degeneration(AMD)underwent a strong improvement in terms of pathophysiology understanding and treatments efficacy monitoring,thank to multimodal imaging techniques.These methodologies are reliable,feasible,easily reproducible,and provide very detailed microstructural information regarding retinal status in a non invasively way.Their introduction in clinical practice opened new frontiers for the ophthalmologists to face macular diseases.One of the most recently introduced technique is optical coherence tomography angiography(OCTA),which offered for the first time the opportunity to study in detail the retinal vascular network without the adoption of dye.Although multimodal imaging is mainly analyzed from the qualitative point of view,in the last years even more advanced quantitative approaches were introduced to further improve the amount of information reached by images analyses.In the context of OCTA,vessel density still represents the most used measure;it provides useful information regarding vascular deficits occurring in macular diseases(2).However,vessel density reductions resulted not pathognomonic of given retinal diseases.
