Coronavirus disease 2019(COVID-19)vaccines are currently approved or authorized to prevent serious outcomes,such as severe disease,hospitalization,and death.The Pfizer-BioNTech vaccine is recommended for everyone aged...Coronavirus disease 2019(COVID-19)vaccines are currently approved or authorized to prevent serious outcomes,such as severe disease,hospitalization,and death.The Pfizer-BioNTech vaccine is recommended for everyone aged five and older in the United States(US)to prevent severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection[1,2].However,it is unclear whether children with a history of multisystem,inflammatory syndrome in children(MIS-C)may be at risk for a MIS-like response following COVID-19 vaccination or SARS-CoV-2 reinfection[2].Therefore,physicians remain uncertain about vaccinating children with a history of MIS-C.This study investigates the occurrence of severe,systemic side effects of COVID-19 vaccines and the recurrence of the MIS-C symptoms in children with a history of MIS-C to overcome vaccine hesitancy.展开更多
文摘Coronavirus disease 2019(COVID-19)vaccines are currently approved or authorized to prevent serious outcomes,such as severe disease,hospitalization,and death.The Pfizer-BioNTech vaccine is recommended for everyone aged five and older in the United States(US)to prevent severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection[1,2].However,it is unclear whether children with a history of multisystem,inflammatory syndrome in children(MIS-C)may be at risk for a MIS-like response following COVID-19 vaccination or SARS-CoV-2 reinfection[2].Therefore,physicians remain uncertain about vaccinating children with a history of MIS-C.This study investigates the occurrence of severe,systemic side effects of COVID-19 vaccines and the recurrence of the MIS-C symptoms in children with a history of MIS-C to overcome vaccine hesitancy.
