Acute fatty liver of pregnancy (AFLP) is a rare obstetric complication, and despite improvements in recognition and management over recent decades, it still carries a high risk of maternal and fetal morbidity and mort...Acute fatty liver of pregnancy (AFLP) is a rare obstetric complication, and despite improvements in recognition and management over recent decades, it still carries a high risk of maternal and fetal morbidity and mortality. Patients typically present in the third trimester with non-specific symptoms, including nausea and vomiting, upper abdominal pain, malaise and anorexia. Initial diagnosis can be challenging due to the sometimes-insidious presentation, as well as the difficulty in distinguishing between AFLP and other conditions seen in pregnancy with overlapping features. We report a case study of a 32-year-old primigravida who presented with mild and non-specific symptoms, and examination findings leading to a timely diagnosis of AFLP were made. This case highlights the importance of early recognition, prompt intervention, and multidisciplinary management to achieve optimal maternal and fetal outcomes.展开更多
文摘Acute fatty liver of pregnancy (AFLP) is a rare obstetric complication, and despite improvements in recognition and management over recent decades, it still carries a high risk of maternal and fetal morbidity and mortality. Patients typically present in the third trimester with non-specific symptoms, including nausea and vomiting, upper abdominal pain, malaise and anorexia. Initial diagnosis can be challenging due to the sometimes-insidious presentation, as well as the difficulty in distinguishing between AFLP and other conditions seen in pregnancy with overlapping features. We report a case study of a 32-year-old primigravida who presented with mild and non-specific symptoms, and examination findings leading to a timely diagnosis of AFLP were made. This case highlights the importance of early recognition, prompt intervention, and multidisciplinary management to achieve optimal maternal and fetal outcomes.
