In 2020,international consensus guidelines recommended renaming a non-alcoholic fatty liver disease(NAFLD)to metabolic-associated fatty liver disease(MAFLD)(1).However,these two terms are not interchangeable.Diagnosis...In 2020,international consensus guidelines recommended renaming a non-alcoholic fatty liver disease(NAFLD)to metabolic-associated fatty liver disease(MAFLD)(1).However,these two terms are not interchangeable.Diagnosis of MAFLD is established while hepatic steatosis(diagnosed by the use of non-invasive methods as well as liver biopsy)is accompanied by overweight/obesity or type 2 diabetes(T2D)or two or more metabolic risk factors,including increased waist circumference(with cut off values specific for the population),arterial hypertension,hypertriglyceridemia,low high-density lipoprotein cholesterol(HDL-C)(<40 mmol/L in women and<50 mmol/L in men),prediabetes(impaired fasting glucose,impaired glucose tolerance or glycated hemoglobin 5.7-6.4%).展开更多
文摘In 2020,international consensus guidelines recommended renaming a non-alcoholic fatty liver disease(NAFLD)to metabolic-associated fatty liver disease(MAFLD)(1).However,these two terms are not interchangeable.Diagnosis of MAFLD is established while hepatic steatosis(diagnosed by the use of non-invasive methods as well as liver biopsy)is accompanied by overweight/obesity or type 2 diabetes(T2D)or two or more metabolic risk factors,including increased waist circumference(with cut off values specific for the population),arterial hypertension,hypertriglyceridemia,low high-density lipoprotein cholesterol(HDL-C)(<40 mmol/L in women and<50 mmol/L in men),prediabetes(impaired fasting glucose,impaired glucose tolerance or glycated hemoglobin 5.7-6.4%).
