Background: The difficulty with histopathology diagnosis is the presence of numerous benign reactive breast lesions with morphological features mimic malignant lesions. Thus, the objective of this study was to assess ...Background: The difficulty with histopathology diagnosis is the presence of numerous benign reactive breast lesions with morphological features mimic malignant lesions. Thus, the objective of this study was to assess the merit of morphological patterns of elastic and reticular fibers in differential diagnosis of benign and malignant breast lesions. Methodology: Fifty biopsies were obtained from females with breast Lesions (25 breast carcinoma and 25 benign lesions), their ages ranging from 17 to 85 years with mean age of 39 years old. Morphologic demonstrations of elastic and reticular fibers were performed using conventional histochemical procedures. Results: Intense grades of elastic fiber staining were achieved with carcinoma tissues. Dwindled grades of elastic fiber staining were detected with fibrocystic changes. Elastic fibers in breast carcinoma are significantly increased compared to benign breast lesions P Conclusion: Histochemical quantifications of elastic and reticular fibers can assist in routine diagnosis of breast lesions. Elastic fibers significantly increase in breast carcinoma compared to benign breast lesions.展开更多
Objective: The objective of this study was to appraise the epidemiology and patterns of malignant lymphoma in Northern Saudi Arabia. Methodology: A full reportage of data regarding malignant lymphoma was retrieved fro...Objective: The objective of this study was to appraise the epidemiology and patterns of malignant lymphoma in Northern Saudi Arabia. Methodology: A full reportage of data regarding malignant lymphoma was retrieved from the King Khalid Hospital, Hail, Northern Saudi Arabia, comprising records of malignant lymphoma from 2009 to 2016. Results: A review of 120 blood cancers records revealed 47/120 (39.2%) cases of lymphomas, 39 (83%) were Non-Hodgkin lymphoma (NHL), 6 (12.8%) were HL and 2 (4.2%) B-cell lymphomas. The overall crude incidence rate CIR) of lymphomas (from 2009 to 2016) was 6.7 per 100,000 persons of the Hail region population. The mean CIR per year was 0.84 per 100,000 persons. Conclusion: The prevalence of malignant lymphoma is relatively higher in northern Saudi Arabia with predominance of NHL amongst elder population.展开更多
文摘Background: The difficulty with histopathology diagnosis is the presence of numerous benign reactive breast lesions with morphological features mimic malignant lesions. Thus, the objective of this study was to assess the merit of morphological patterns of elastic and reticular fibers in differential diagnosis of benign and malignant breast lesions. Methodology: Fifty biopsies were obtained from females with breast Lesions (25 breast carcinoma and 25 benign lesions), their ages ranging from 17 to 85 years with mean age of 39 years old. Morphologic demonstrations of elastic and reticular fibers were performed using conventional histochemical procedures. Results: Intense grades of elastic fiber staining were achieved with carcinoma tissues. Dwindled grades of elastic fiber staining were detected with fibrocystic changes. Elastic fibers in breast carcinoma are significantly increased compared to benign breast lesions P Conclusion: Histochemical quantifications of elastic and reticular fibers can assist in routine diagnosis of breast lesions. Elastic fibers significantly increase in breast carcinoma compared to benign breast lesions.
文摘Objective: The objective of this study was to appraise the epidemiology and patterns of malignant lymphoma in Northern Saudi Arabia. Methodology: A full reportage of data regarding malignant lymphoma was retrieved from the King Khalid Hospital, Hail, Northern Saudi Arabia, comprising records of malignant lymphoma from 2009 to 2016. Results: A review of 120 blood cancers records revealed 47/120 (39.2%) cases of lymphomas, 39 (83%) were Non-Hodgkin lymphoma (NHL), 6 (12.8%) were HL and 2 (4.2%) B-cell lymphomas. The overall crude incidence rate CIR) of lymphomas (from 2009 to 2016) was 6.7 per 100,000 persons of the Hail region population. The mean CIR per year was 0.84 per 100,000 persons. Conclusion: The prevalence of malignant lymphoma is relatively higher in northern Saudi Arabia with predominance of NHL amongst elder population.