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Mathematical Model of HIV-1 Circulating Recombinants Forms in Mali
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作者 Mahamadou Alassane amadou mahamane +1 位作者 Ouateni Diallo Jerome Pousin 《Open Journal of Modelling and Simulation》 2015年第4期137-145,共9页
In this paper, we propose a determinist mathematical model for the co-circulating into two circulating recombinants forms (CRFs) Of HIV-disease in Mali. We divide the sexually active population within three compartmen... In this paper, we propose a determinist mathematical model for the co-circulating into two circulating recombinants forms (CRFs) Of HIV-disease in Mali. We divide the sexually active population within three compartments (susceptible, CRF-1 infected and CRF-2 or CRF-12 infected) and study the dynamical behavior of this model. Then, we define a basic reproduction number of the CRF-2 or CRF-12 infected individuals R0 and shown that the CRF-2 or CRF-12 infected-free equilibrium is locally-asymptotically stable if R0 1 (thus the CRF-2 or CRF-12 infected invade in the population). Fur-thermore, we prove that under certain conditions on the parameters of the model the controllability of CRF-2 or CRF-12 infected with regard to the CRF-1 infected. Numerical simulations are given to illustrate the results. 展开更多
关键词 Asymptotic Stability Basic Reproduction Number of the CRF-2 or CRF-12 Infected CONTROLLABILITY
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