Introduction: The coronavirus, SARS-CoV-2, is the pathogen responsible for an acute respiratory distress syndrome that broke out in the Wuhan region and became a pandemic in early 2020. The clinical presentation of CO...Introduction: The coronavirus, SARS-CoV-2, is the pathogen responsible for an acute respiratory distress syndrome that broke out in the Wuhan region and became a pandemic in early 2020. The clinical presentation of COVID-19 is polymorphic, dominated by respiratory symptoms and may be associated with cardiovascular, digestive and renal complications. The prognosis depends mainly on the patient’s condition. Acute kidney injury (AKI) during severe SARS CoV-2 infection is frequent, multifactorial and associated with excess mortality. Its pathophysiology has not been fully elucidated, and seems to involve both direct and indirect mechanisms. The aim of our work is to describe the epidemiological, clinical, paraclinical and therapeutic profile of patients presenting with AKI and confirmed COVID-19 disease, and determine the prognostic factors associated with death. Material and Methods: This was a retrospective study conducted at IBN SINA Hospital, Rabat, between March 2020 and November 2021. We included patients with confirmed SARS-CoV-2 infection who developed AKI either on admission or during hospitalization. Results: We enrolled 95 patients with a mean age of 68 ± 13 years and a M/F sex ratio of 1.9. Diabetes was present in 33.7% of cases and hypertension in 32.6%. Most patients had influenzalike illness, lymphopenia and hyperferritinemia. Median creatinine on admission was 32 mg/l [17 - 64]. Temporary catheter hemodialysis was used in 21% of cases, with hyperkalemia for purification and ultrafiltration. There were 63 deaths, it was statically significantly related (p Conclusion: AKI in COVID-19 is multifactorial, and may be secondary to sepsis, hemodynamic failure or direct viral toxicity to the kidney. In our study, mortality was secondary to viral toxicity, clinical presentation, intensive care unit management and recourse to hemodialysis.展开更多
Background: Pregnancy is typically accompanied by an increase of micronutrient requirements in general and especially iron. This increased need may be an additional risk factor for developing anemia. Purpose of the st...Background: Pregnancy is typically accompanied by an increase of micronutrient requirements in general and especially iron. This increased need may be an additional risk factor for developing anemia. Purpose of the study: The aim of this study is to provide data on the prevalence of anemia of pregnancy in the maternity ward of the regional hospital in the city of Temara, and examine risk factors that may expose women to anemia during pregnancy. Materiel and Methods: A prospective cross-sectional study of a year was conducted to the hospital Sidi Lahcen in the city of Temara. Sociodemographic and nutritional data were collected through a questionnaire, obstetric and medical histories of women in labor and the results of biological tests were recorded from the patient obstetric file. Results: Among the 849 women surveyed, 690 (82%) had performed a blood count, and among these 117 (16.8%) were found anemic, with the following proportions: 57.6% had mild anemia, 41.5% had moderate anemia and a minority (0.8%) had severe anemia. The pregnant women aged over 35 years were the most exposed to anemia during pregnancy (47%) compared with younger women (p < 0.001). Women who had a history of anemia aside from pregnancy and those who had anemia in earlier pregnancies were more prone to developing anemia in the current pregnancy with a statistically significant difference (p < 0.001). The number of pregnancies, number of previous abortions and place of residence had no influence on the occurrence of anemia of pregnancy. The consumption of fortified flour with iron and vitamins as well as consuming iron rich foods was not a protective factor against the development of anemia of pregnancy. Tea consumption near the meal was not a factor exposing to anemia during pregnancy. Conclusion: Anemia is a public health problem in Morocco. Evidence from our study emphasizes the need to implement educational programs to improve the nutritional knowledge and sensitization of women.展开更多
文摘Introduction: The coronavirus, SARS-CoV-2, is the pathogen responsible for an acute respiratory distress syndrome that broke out in the Wuhan region and became a pandemic in early 2020. The clinical presentation of COVID-19 is polymorphic, dominated by respiratory symptoms and may be associated with cardiovascular, digestive and renal complications. The prognosis depends mainly on the patient’s condition. Acute kidney injury (AKI) during severe SARS CoV-2 infection is frequent, multifactorial and associated with excess mortality. Its pathophysiology has not been fully elucidated, and seems to involve both direct and indirect mechanisms. The aim of our work is to describe the epidemiological, clinical, paraclinical and therapeutic profile of patients presenting with AKI and confirmed COVID-19 disease, and determine the prognostic factors associated with death. Material and Methods: This was a retrospective study conducted at IBN SINA Hospital, Rabat, between March 2020 and November 2021. We included patients with confirmed SARS-CoV-2 infection who developed AKI either on admission or during hospitalization. Results: We enrolled 95 patients with a mean age of 68 ± 13 years and a M/F sex ratio of 1.9. Diabetes was present in 33.7% of cases and hypertension in 32.6%. Most patients had influenzalike illness, lymphopenia and hyperferritinemia. Median creatinine on admission was 32 mg/l [17 - 64]. Temporary catheter hemodialysis was used in 21% of cases, with hyperkalemia for purification and ultrafiltration. There were 63 deaths, it was statically significantly related (p Conclusion: AKI in COVID-19 is multifactorial, and may be secondary to sepsis, hemodynamic failure or direct viral toxicity to the kidney. In our study, mortality was secondary to viral toxicity, clinical presentation, intensive care unit management and recourse to hemodialysis.
文摘Background: Pregnancy is typically accompanied by an increase of micronutrient requirements in general and especially iron. This increased need may be an additional risk factor for developing anemia. Purpose of the study: The aim of this study is to provide data on the prevalence of anemia of pregnancy in the maternity ward of the regional hospital in the city of Temara, and examine risk factors that may expose women to anemia during pregnancy. Materiel and Methods: A prospective cross-sectional study of a year was conducted to the hospital Sidi Lahcen in the city of Temara. Sociodemographic and nutritional data were collected through a questionnaire, obstetric and medical histories of women in labor and the results of biological tests were recorded from the patient obstetric file. Results: Among the 849 women surveyed, 690 (82%) had performed a blood count, and among these 117 (16.8%) were found anemic, with the following proportions: 57.6% had mild anemia, 41.5% had moderate anemia and a minority (0.8%) had severe anemia. The pregnant women aged over 35 years were the most exposed to anemia during pregnancy (47%) compared with younger women (p < 0.001). Women who had a history of anemia aside from pregnancy and those who had anemia in earlier pregnancies were more prone to developing anemia in the current pregnancy with a statistically significant difference (p < 0.001). The number of pregnancies, number of previous abortions and place of residence had no influence on the occurrence of anemia of pregnancy. The consumption of fortified flour with iron and vitamins as well as consuming iron rich foods was not a protective factor against the development of anemia of pregnancy. Tea consumption near the meal was not a factor exposing to anemia during pregnancy. Conclusion: Anemia is a public health problem in Morocco. Evidence from our study emphasizes the need to implement educational programs to improve the nutritional knowledge and sensitization of women.
