Congenital unilateral lower lip palsy(CULLP),or congenital hypoplasia of the depressor anguli oris muscle,also known as asymmetric crying facies,is a rare condition that results in asymmetry of the lower lip during sm...Congenital unilateral lower lip palsy(CULLP),or congenital hypoplasia of the depressor anguli oris muscle,also known as asymmetric crying facies,is a rare condition that results in asymmetry of the lower lip during smiling,laughing,and crying.Although the etiology is unknown,weakness of the depressor labii inferioris(DLI)muscle is implicated as a contributing factor.Currently,no well-established treatment options are available.This case report describes an 18-year-old male patient diagnosed with CULLP.Physical examination revealed a symmetric face at rest,but asymmetry when smiling and opening the mouth.Following the administration of lidocaine into the affected DLI muscle,the patient’s smile and lower lip symmetry were immediately restored without any adverse effects.Subsequently,administration of botulinum toxin for neuromodulation of the DLI muscle led to a significant improvement in symmetry and oral function within 2 weeks,which was sustained at 1 month and 3 months post-treatment.No adverse effects were reported,and both patients and families expressed high satisfaction with the outcomes.This case highlights the potential use of neuromodulation as a minimally invasive and effective treatment for CULLP.展开更多
With increasing population and limitation of availability of land,tall buildings supported on piled raft foundations are increasingly used in the modern world.To increase the ratio of floor area to height,and to fulfi...With increasing population and limitation of availability of land,tall buildings supported on piled raft foundations are increasingly used in the modern world.To increase the ratio of floor area to height,and to fulfill storage and parking facilities requirements,these tall buildings usually have more than one basement level.Conventionally,during the foundation design,engineers have not considered the basement wall contribution to resisting lateral load induced by earthquake or wind and this can result in an uneconomical construction of foundations.In this research work,an experimental study was performed on small-scale models,in order to study basement wall contribution,and the raft contribution including for piled raft foundations,to resisting lateral load.Three configurations of piles in 2×2,2×3,and 3×3 patterns were tested as a pile group,piled raft and piled raft with a basement wall.Results show that when a basement wall is present,the lateral displacement decreases and the demand on each pile decreases.The piled raft design can become more economical for tall buildings if the basement’s walls are taken into account.展开更多
文摘Congenital unilateral lower lip palsy(CULLP),or congenital hypoplasia of the depressor anguli oris muscle,also known as asymmetric crying facies,is a rare condition that results in asymmetry of the lower lip during smiling,laughing,and crying.Although the etiology is unknown,weakness of the depressor labii inferioris(DLI)muscle is implicated as a contributing factor.Currently,no well-established treatment options are available.This case report describes an 18-year-old male patient diagnosed with CULLP.Physical examination revealed a symmetric face at rest,but asymmetry when smiling and opening the mouth.Following the administration of lidocaine into the affected DLI muscle,the patient’s smile and lower lip symmetry were immediately restored without any adverse effects.Subsequently,administration of botulinum toxin for neuromodulation of the DLI muscle led to a significant improvement in symmetry and oral function within 2 weeks,which was sustained at 1 month and 3 months post-treatment.No adverse effects were reported,and both patients and families expressed high satisfaction with the outcomes.This case highlights the potential use of neuromodulation as a minimally invasive and effective treatment for CULLP.
文摘With increasing population and limitation of availability of land,tall buildings supported on piled raft foundations are increasingly used in the modern world.To increase the ratio of floor area to height,and to fulfill storage and parking facilities requirements,these tall buildings usually have more than one basement level.Conventionally,during the foundation design,engineers have not considered the basement wall contribution to resisting lateral load induced by earthquake or wind and this can result in an uneconomical construction of foundations.In this research work,an experimental study was performed on small-scale models,in order to study basement wall contribution,and the raft contribution including for piled raft foundations,to resisting lateral load.Three configurations of piles in 2×2,2×3,and 3×3 patterns were tested as a pile group,piled raft and piled raft with a basement wall.Results show that when a basement wall is present,the lateral displacement decreases and the demand on each pile decreases.The piled raft design can become more economical for tall buildings if the basement’s walls are taken into account.
