We report a 43-year-old man who presented with a right painful shoulder mass and bilateral lung masses in computed tomography(CT).Scapular mass was excised and pathology report demonstrated high-grade metastatic tumor...We report a 43-year-old man who presented with a right painful shoulder mass and bilateral lung masses in computed tomography(CT).Scapular mass was excised and pathology report demonstrated high-grade metastatic tumor.Same side lung biopsy and histopathological study characterized tuberculosis but biopsy of the left lung lesion identified adenocarcinoma of the lung.The final diagnosis was right scapular metastatic lesion from left lung adenocarcinoma.Musculoskeletal symptoms are commonly encountered in lung malignancies due to paraneoplastic syndrome or hematogenous metastasis but scapular metastasis on the other side as the presentation of lung cancer is extremely rare.展开更多
BACKGROUND Coronavirus disease 2019(COVID-19)is a novel very contagious infection which was designated a pandemic in all countries of the world in April 2020.Its presentation varies from mild to severe infection,but t...BACKGROUND Coronavirus disease 2019(COVID-19)is a novel very contagious infection which was designated a pandemic in all countries of the world in April 2020.Its presentation varies from mild to severe infection,but the majority of infected patients have mild manifestations.Many therapeutic choices have been suggested to treat the infection,but none are fully effective.CASE SUMMARY Herein we present a 26-year-old woman with a twin pregnancy at 36 wk and one day gestation with confirmed COVID-19 who responded dramatically to convalescent plasma therapy(CPT)and Favipiravir.CONCLUSION Although this case report shows the efficacy of CPT in addition to usual medications used for COVID-19,there are many questions that need to be answered regarding dosage,para-clinical efficacy,side effects and combination therapy.展开更多
BACKGROUND In chest computed tomography(CT)scan,bilateral peripheral multifocal groundglass opacities,linear opacities,reversed halo sign,and crazy-paving pattern are suggestive for coronavirus disease 2019(COVID-19)i...BACKGROUND In chest computed tomography(CT)scan,bilateral peripheral multifocal groundglass opacities,linear opacities,reversed halo sign,and crazy-paving pattern are suggestive for coronavirus disease 2019(COVID-19)in clinically suspicious cases,but they are not specific for the diagnosis,as other viral pneumonias,like influenza and some viral pneumonia may show similar imaging findings.AIM To find a specific imaging feature of the disease would be a welcome guide in diagnosis and management of challenging cases.METHODS Chest CT imaging findings of 650 patients admitted to a university Hospital in Tehran,Iran between January 2020 and July 2020 with confirmed COVID-19 infection by RT-PCR were reviewed by two expert radiologists.In addition to common non-specific imaging findings of COVID-19 pneumonia,radiologic characteristics of“pulmonary target sign”(PTS)were assessed.PTS is defined as a circular appearance of non-involved pulmonary parenchyma,which encompass a central hyperdense dot surrounded by ground-glass or alveolar opacities.RESULTS PTS were presented in 32 cases(frequency 4.9%).The location of the lesions in 31 of the 32 cases(96.8%)was peripheral,while 4 of the 31 cases had lesions both peripherally and centrally.In 25 cases,the lesions were located near the pleural surface and considered pleural based and half of the lesions(at least one lesion)were in the lower segments and lobes of the lungs.22 cases had multiple lesions with a>68%frequency.More than 87%of cases had an adjacent bronchovascular bundle.Ground-glass opacities were detectable adjacent or close to the lesions in 30 cases(93%)and only in 7 cases(21%)was consolidation adjacent to the lesions.CONCLUSION Although it is not frequent in COVID-19,familiarity with this feature may help radiologists and physicians distinguish the disease from other viral and noninfectious pneumonias in challenging cases.展开更多
文摘We report a 43-year-old man who presented with a right painful shoulder mass and bilateral lung masses in computed tomography(CT).Scapular mass was excised and pathology report demonstrated high-grade metastatic tumor.Same side lung biopsy and histopathological study characterized tuberculosis but biopsy of the left lung lesion identified adenocarcinoma of the lung.The final diagnosis was right scapular metastatic lesion from left lung adenocarcinoma.Musculoskeletal symptoms are commonly encountered in lung malignancies due to paraneoplastic syndrome or hematogenous metastasis but scapular metastasis on the other side as the presentation of lung cancer is extremely rare.
文摘BACKGROUND Coronavirus disease 2019(COVID-19)is a novel very contagious infection which was designated a pandemic in all countries of the world in April 2020.Its presentation varies from mild to severe infection,but the majority of infected patients have mild manifestations.Many therapeutic choices have been suggested to treat the infection,but none are fully effective.CASE SUMMARY Herein we present a 26-year-old woman with a twin pregnancy at 36 wk and one day gestation with confirmed COVID-19 who responded dramatically to convalescent plasma therapy(CPT)and Favipiravir.CONCLUSION Although this case report shows the efficacy of CPT in addition to usual medications used for COVID-19,there are many questions that need to be answered regarding dosage,para-clinical efficacy,side effects and combination therapy.
文摘BACKGROUND In chest computed tomography(CT)scan,bilateral peripheral multifocal groundglass opacities,linear opacities,reversed halo sign,and crazy-paving pattern are suggestive for coronavirus disease 2019(COVID-19)in clinically suspicious cases,but they are not specific for the diagnosis,as other viral pneumonias,like influenza and some viral pneumonia may show similar imaging findings.AIM To find a specific imaging feature of the disease would be a welcome guide in diagnosis and management of challenging cases.METHODS Chest CT imaging findings of 650 patients admitted to a university Hospital in Tehran,Iran between January 2020 and July 2020 with confirmed COVID-19 infection by RT-PCR were reviewed by two expert radiologists.In addition to common non-specific imaging findings of COVID-19 pneumonia,radiologic characteristics of“pulmonary target sign”(PTS)were assessed.PTS is defined as a circular appearance of non-involved pulmonary parenchyma,which encompass a central hyperdense dot surrounded by ground-glass or alveolar opacities.RESULTS PTS were presented in 32 cases(frequency 4.9%).The location of the lesions in 31 of the 32 cases(96.8%)was peripheral,while 4 of the 31 cases had lesions both peripherally and centrally.In 25 cases,the lesions were located near the pleural surface and considered pleural based and half of the lesions(at least one lesion)were in the lower segments and lobes of the lungs.22 cases had multiple lesions with a>68%frequency.More than 87%of cases had an adjacent bronchovascular bundle.Ground-glass opacities were detectable adjacent or close to the lesions in 30 cases(93%)and only in 7 cases(21%)was consolidation adjacent to the lesions.CONCLUSION Although it is not frequent in COVID-19,familiarity with this feature may help radiologists and physicians distinguish the disease from other viral and noninfectious pneumonias in challenging cases.
