AIM：To estimate the overall prevalence of diabetic retinopathy（DR） in Iran by a systematic review and Metaanalysis.METHODS：We conducted a search of all published literature on diabetic patients for the prevalence ...AIM：To estimate the overall prevalence of diabetic retinopathy（DR） in Iran by a systematic review and Metaanalysis.METHODS：We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, Pub Med, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals（CI） were calculated using random effects models.RESULTS：Thirty-one studies involving 23 729 patients with type Ⅰ and Ⅱ diabetes were included. The publication bias assumption for prevalence of DR was rejected by Begg and Egger tests（P=0.825, P=0.057, respectively）. The results of Cochran test and I^2 statistics showed considerable heterogeneity for prevalence of DR（Q=1278.21, d.f.=30, P〈0.001 and I^2=97.7%）. The prevalence of DR, non-proliferative diabetic retinopathy（NPDR） and proliferative diabetic retinopathy（PDR） in Iranian diabetic patients were 41.9%（95% CI：35.6-48.2）, 32.2%（95% CI：28.7-35.8）, and 13.2%（95% CI：8.3-18.1）, respectively. CONCLUSION：The prevalence of DR in Iran appears a little high. NPDR was more common. This study highlights the necessity for DR screening and management in diabetic patients in Iran.展开更多
文摘AIM：To estimate the overall prevalence of diabetic retinopathy（DR） in Iran by a systematic review and Metaanalysis.METHODS：We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, Pub Med, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals（CI） were calculated using random effects models.RESULTS：Thirty-one studies involving 23 729 patients with type Ⅰ and Ⅱ diabetes were included. The publication bias assumption for prevalence of DR was rejected by Begg and Egger tests（P=0.825, P=0.057, respectively）. The results of Cochran test and I^2 statistics showed considerable heterogeneity for prevalence of DR（Q=1278.21, d.f.=30, P〈0.001 and I^2=97.7%）. The prevalence of DR, non-proliferative diabetic retinopathy（NPDR） and proliferative diabetic retinopathy（PDR） in Iranian diabetic patients were 41.9%（95% CI：35.6-48.2）, 32.2%（95% CI：28.7-35.8）, and 13.2%（95% CI：8.3-18.1）, respectively. CONCLUSION：The prevalence of DR in Iran appears a little high. NPDR was more common. This study highlights the necessity for DR screening and management in diabetic patients in Iran.
