Objective:Different studies have been performed on the prevalence of tick-borne pathogens in different areas of Iran;however,as far as our knowledge,there is no regional meta-analysis available for consideration and e...Objective:Different studies have been performed on the prevalence of tick-borne pathogens in different areas of Iran;however,as far as our knowledge,there is no regional meta-analysis available for consideration and estimation of tick species infected with different pathogens in Iran.Methods:In this review,among different databases,a total of 95 publications were included,and the infection of different tick species to different tick-borne pathogens was determined;furthermore,presence of pathogens(with 95%confidence intervals)in tick vectors was calculated separately for each province,using Comprehensive Meta-Analysis version 2(Biostat,USA).Results:Totally,among all 95 studies,5673 out of 33521 investigated ticks were positive according to different detection methods.Overall estimated presence of pathogens in tick vectors in Iran was 8.6%(95%CI 7.0%-10.6%,P<0.001).Of all 46 species of ticks in 10 genera in Iran,28 species in 9 genera,including Alveonasus,Argas,Boophilus,Dermacentor,Haemaphysalis,Hyalomma,Ixodes,Ornithodoros,and Rhipicephalus were infected with at least 20 pathogens in 10 genera including Aegyptianella,Anaplasma,Babesia,Borrelia,Brucella,Orthonairovirus[CrimeanCongo hemorrhagic fever virus(CCHFV)],Coxiella,Ehrlichia,Rickettsia and Theileria in 26 provinces of Iran.The presence of pathogens in ticks collected in western Iran was more than other regions.Hyalomma anatolicum(20.35%),Rhipicephalus sanguineus(15.00%),and Rhipicephalus bursa(14.08%)were the most prevalent infected ticks for different pathogens.In addition,most literatures were related to CCHFV and Theileria/Babesia spp.Conclusions:Public health and veterinary professionals should be aware of diagnosing possible diseases or outbreaks in vertebrates.展开更多
文摘Objective:Different studies have been performed on the prevalence of tick-borne pathogens in different areas of Iran;however,as far as our knowledge,there is no regional meta-analysis available for consideration and estimation of tick species infected with different pathogens in Iran.Methods:In this review,among different databases,a total of 95 publications were included,and the infection of different tick species to different tick-borne pathogens was determined;furthermore,presence of pathogens(with 95%confidence intervals)in tick vectors was calculated separately for each province,using Comprehensive Meta-Analysis version 2(Biostat,USA).Results:Totally,among all 95 studies,5673 out of 33521 investigated ticks were positive according to different detection methods.Overall estimated presence of pathogens in tick vectors in Iran was 8.6%(95%CI 7.0%-10.6%,P<0.001).Of all 46 species of ticks in 10 genera in Iran,28 species in 9 genera,including Alveonasus,Argas,Boophilus,Dermacentor,Haemaphysalis,Hyalomma,Ixodes,Ornithodoros,and Rhipicephalus were infected with at least 20 pathogens in 10 genera including Aegyptianella,Anaplasma,Babesia,Borrelia,Brucella,Orthonairovirus[CrimeanCongo hemorrhagic fever virus(CCHFV)],Coxiella,Ehrlichia,Rickettsia and Theileria in 26 provinces of Iran.The presence of pathogens in ticks collected in western Iran was more than other regions.Hyalomma anatolicum(20.35%),Rhipicephalus sanguineus(15.00%),and Rhipicephalus bursa(14.08%)were the most prevalent infected ticks for different pathogens.In addition,most literatures were related to CCHFV and Theileria/Babesia spp.Conclusions:Public health and veterinary professionals should be aware of diagnosing possible diseases or outbreaks in vertebrates.
