A p-type transition metal dichalcogenide(WS2)was synthesized and hybridized with graphene oxide via a simple hydrothermal method.The as-prepared material was used to modify a glassy carbon electrode for the fabricatio...A p-type transition metal dichalcogenide(WS2)was synthesized and hybridized with graphene oxide via a simple hydrothermal method.The as-prepared material was used to modify a glassy carbon electrode for the fabrication of a simple,stable,and repeatable methylene blue-labeled“signal-off”aptasensor used for the sensitive determination of very low amounts of sodium diclofenac(DCF).The synthetic material,modification process,and role of WS2 in the current response enhancement were studied by X-ray diffraction,energy-dispersive X-ray spectroscopy,field emission scanning electron microscopy,high resolution transmission electron microscopy,Hall effect,cyclic voltammetry,differential pulse voltammetry,and electrochemical impedance spectroscopy.Subsequently,a wide linear range of DCF concentration(0.5-300 nmol/L),very low limit of detection(0.23 nmol/L),and good selectivity were obtained using the differential pulse voltammetry method with the assembled aptasensor.Finally,the fabricated aptasensor was successfully developed for physiological real samples with significant recoveries.展开更多
文摘A p-type transition metal dichalcogenide(WS2)was synthesized and hybridized with graphene oxide via a simple hydrothermal method.The as-prepared material was used to modify a glassy carbon electrode for the fabrication of a simple,stable,and repeatable methylene blue-labeled“signal-off”aptasensor used for the sensitive determination of very low amounts of sodium diclofenac(DCF).The synthetic material,modification process,and role of WS2 in the current response enhancement were studied by X-ray diffraction,energy-dispersive X-ray spectroscopy,field emission scanning electron microscopy,high resolution transmission electron microscopy,Hall effect,cyclic voltammetry,differential pulse voltammetry,and electrochemical impedance spectroscopy.Subsequently,a wide linear range of DCF concentration(0.5-300 nmol/L),very low limit of detection(0.23 nmol/L),and good selectivity were obtained using the differential pulse voltammetry method with the assembled aptasensor.Finally,the fabricated aptasensor was successfully developed for physiological real samples with significant recoveries.
