First Enantioselective Synthesis of Isoamericanol A and Isoamericanin A

The first enantioselective synthesis approach to two chiral 1,4-benzodioxane neolignans isoamericanol A and isoamericanin A was reported.

Total Synthesis of Machilin A

Machilin A, isolated from the bark and root of Machilus thunbergii Sieb. et Zucc., was synthesized in eight steps from piperonal, with the coupling reaction as a key step.