Internet of things (IoT) is a developing technology with a lot of scope in the future. It can ease various different tasks for us. On one hand, IoT is useful for us, on the other hand, it has many serious security thr...Internet of things (IoT) is a developing technology with a lot of scope in the future. It can ease various different tasks for us. On one hand, IoT is useful for us, on the other hand, it has many serious security threats, like data breaches, side-channel attacks, and virus and data authentication. Classical cryptographic algorithms, like the Rivest-Shamir-Adleman (RSA) algorithm, work well under the classical computers. But the technology is slowly shifting towards quantum computing, which has immense processing power and is more than enough to break the current cryptographic algorithms easily. So it is required that we have to design quantum cryptographic algorithms to prevent our systems from security breaches even before quantum computers come in the market for commercial uses. IoT will also be one of the disciplines, which needs to be secured to prevent any malicious activities. In this paper, we review the common security threats in IoT and the presently available solutions with their drawbacks. Then quantum cryptography is introduced with some of its variations. And finally, the analysis has been carried out in terms of the pros and cons of implementing quantum cryptography for IoT security.展开更多
Background:Pathological involvement of the seminal vesicle poses a treatment dilemma following robotic prostatectomy.Margin status plays an important role in deciding further management.A wide range of treatment optio...Background:Pathological involvement of the seminal vesicle poses a treatment dilemma following robotic prostatectomy.Margin status plays an important role in deciding further management.A wide range of treatment options are available,including active monitoring,adjuvant radiotherapy,salvage radiotherapy,and occasionally androgen deprivation therapy.Patients undergoing postoperative radiotherapy tend to have higher risk of urinary and bowel morbidities.The recent RADICALS-RT concluded that adjuvant radiotherapy did not have any benefit compared with salvage radiotherapy.We aim to audit the incidence,margin status,and management of T3b cancer cases at our center.Materials and methods:A retrospective analysis was conducted of all patients diagnosed with pathological T3b(pT3b)prostate cancer following robotic-assisted laparoscopic prostatectomy from January 2012 to July 2020.Preoperative parameters analyzed included prostate-specific antigen(PSA),T stage,and age.A chi-square test and 2-tailed t test were used to determine the relationship between categorical and continuous variables,respectively.Kaplan-Meier survival curves were generated to assess overall survival in patients with pT3b prostate cancer and used to compare unadjusted progression-free survival among those who underwent adjuvant and salvage radiotherapy.Results:A total of 83(5%)of 1665 patients who underwent robotic prostatectomy were diagnosed with pT3b prostate cancer between January 2012 and July 2020.Among these,36 patients(44%)did not receive any radiotherapy during follow-up,compared with 26 patients(31%)who received adjuvant radiotherapy and 21(25%)who received salvage radiotherapy.The median age of our cohort was 64(SD,6.4)years.Mean PSA at presentation was 12.7 pg/L.Positive margins were seen in 36 patients(43%);however,there was no statistically significant difference between treatment groups(p=0.49).The median overall survival was 96%.There was no significant difference between the adjuvant and salvage groups in terms of biochemical progression-free survival(p=0.66).Five-year biochemical progression-free survival was 94%for those in the adjuvant radiotherapy group and 97%for those in the salvage radiotherapy group.Conclusions:Our audit corroborates with the recently concluded RADICALS-RT study,although we had fewer patients with positive margins.Radiotherapy can be avoided in patients with T3b prostate cancer,even if margin is positive,until there is definitive evidence of PSA recurrence.In keeping with the conclusion of RADICALS-RT,salvage radiotherapy may be preferable to adjuvant radiotherapy.展开更多
文摘Internet of things (IoT) is a developing technology with a lot of scope in the future. It can ease various different tasks for us. On one hand, IoT is useful for us, on the other hand, it has many serious security threats, like data breaches, side-channel attacks, and virus and data authentication. Classical cryptographic algorithms, like the Rivest-Shamir-Adleman (RSA) algorithm, work well under the classical computers. But the technology is slowly shifting towards quantum computing, which has immense processing power and is more than enough to break the current cryptographic algorithms easily. So it is required that we have to design quantum cryptographic algorithms to prevent our systems from security breaches even before quantum computers come in the market for commercial uses. IoT will also be one of the disciplines, which needs to be secured to prevent any malicious activities. In this paper, we review the common security threats in IoT and the presently available solutions with their drawbacks. Then quantum cryptography is introduced with some of its variations. And finally, the analysis has been carried out in terms of the pros and cons of implementing quantum cryptography for IoT security.
文摘Background:Pathological involvement of the seminal vesicle poses a treatment dilemma following robotic prostatectomy.Margin status plays an important role in deciding further management.A wide range of treatment options are available,including active monitoring,adjuvant radiotherapy,salvage radiotherapy,and occasionally androgen deprivation therapy.Patients undergoing postoperative radiotherapy tend to have higher risk of urinary and bowel morbidities.The recent RADICALS-RT concluded that adjuvant radiotherapy did not have any benefit compared with salvage radiotherapy.We aim to audit the incidence,margin status,and management of T3b cancer cases at our center.Materials and methods:A retrospective analysis was conducted of all patients diagnosed with pathological T3b(pT3b)prostate cancer following robotic-assisted laparoscopic prostatectomy from January 2012 to July 2020.Preoperative parameters analyzed included prostate-specific antigen(PSA),T stage,and age.A chi-square test and 2-tailed t test were used to determine the relationship between categorical and continuous variables,respectively.Kaplan-Meier survival curves were generated to assess overall survival in patients with pT3b prostate cancer and used to compare unadjusted progression-free survival among those who underwent adjuvant and salvage radiotherapy.Results:A total of 83(5%)of 1665 patients who underwent robotic prostatectomy were diagnosed with pT3b prostate cancer between January 2012 and July 2020.Among these,36 patients(44%)did not receive any radiotherapy during follow-up,compared with 26 patients(31%)who received adjuvant radiotherapy and 21(25%)who received salvage radiotherapy.The median age of our cohort was 64(SD,6.4)years.Mean PSA at presentation was 12.7 pg/L.Positive margins were seen in 36 patients(43%);however,there was no statistically significant difference between treatment groups(p=0.49).The median overall survival was 96%.There was no significant difference between the adjuvant and salvage groups in terms of biochemical progression-free survival(p=0.66).Five-year biochemical progression-free survival was 94%for those in the adjuvant radiotherapy group and 97%for those in the salvage radiotherapy group.Conclusions:Our audit corroborates with the recently concluded RADICALS-RT study,although we had fewer patients with positive margins.Radiotherapy can be avoided in patients with T3b prostate cancer,even if margin is positive,until there is definitive evidence of PSA recurrence.In keeping with the conclusion of RADICALS-RT,salvage radiotherapy may be preferable to adjuvant radiotherapy.