期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Luminal androgen receptor(LAR)subtype of triple-negative breast cancer:molecular,morphological,and clinical features 被引量:2
1
作者 Sergey VTORUSHIN anastasia dulesova Nadezhda KRAKHMAL 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2022年第8期617-624,共8页
According to the classification presented by Lehmann BD(2016),triple-negative breast cancer(TNBC)is a heterogeneous group of malignant tumors with four specific subtypes:basal-like(subtype 1 and subtype 2),mesenchymal... According to the classification presented by Lehmann BD(2016),triple-negative breast cancer(TNBC)is a heterogeneous group of malignant tumors with four specific subtypes:basal-like(subtype 1 and subtype 2),mesenchymal,and luminal androgen receptor(LAR)subtypes.The basal-like subtypes of carcinomas predominate in this group,accounting for up to 80%of all cases.Despite the significantly lower proportions of mesenchymal and LAR variants in the group of breast carcinomas with a TNBC profile,such tumors are characterized by aggressive biological behavior.To this end,the LAR subtype is of particular interest,since the literature on such tumors presents different and even contradictory data concerning the disease course and prognosis.This review is devoted to the analysis of the relevant literature,reflecting the main results of studies on the molecular properties and clinical features of the disease course of LAR-type TNBC carcinomas. 展开更多
关键词 Luminal androgen receptor(LAR)subtype Triple-negative breast cancer(TNBC) Androgen receptor(AR) PROGNOSIS
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部