5-Fluorouracil(5-FU)is an antimetabolite chemotherapeutic agent that is US Food and Drug Administration(FDA)indicated for use in a variety of neoplasms and is a staple agent in many chemotherapeutic regimens.An import...5-Fluorouracil(5-FU)is an antimetabolite chemotherapeutic agent that is US Food and Drug Administration(FDA)indicated for use in a variety of neoplasms and is a staple agent in many chemotherapeutic regimens.An important adverse effect of 5-FU is cardiotoxicity.There is a wide spectrum of clinical presentation of 5-FU cardiotoxicity from asymptomatic electrocardiogram(ECG)changes to myocardial infarction that clinicians must be aware of when caring for patients receiving this agent.展开更多
文摘5-Fluorouracil(5-FU)is an antimetabolite chemotherapeutic agent that is US Food and Drug Administration(FDA)indicated for use in a variety of neoplasms and is a staple agent in many chemotherapeutic regimens.An important adverse effect of 5-FU is cardiotoxicity.There is a wide spectrum of clinical presentation of 5-FU cardiotoxicity from asymptomatic electrocardiogram(ECG)changes to myocardial infarction that clinicians must be aware of when caring for patients receiving this agent.
