Background:Acre has reported the highest incidence of American cutaneous leishmaniasis(ACL)in Brazil in recent years.The present study seeks to identify high and low risk agglomerations of ACL in space and space-time ...Background:Acre has reported the highest incidence of American cutaneous leishmaniasis(ACL)in Brazil in recent years.The present study seeks to identify high and low risk agglomerations of ACL in space and space-time during the period from 2007 to 2013 in Acre,and also to characterize the occurrence of the disease in time and according to sociodemographic variables.Methods:This is an ecological study,the study population of which consisted of autochthonous ACL cases notified in the municipalities of Acre by an epidemiological surveillance system.Scan statistics of SaTScan^(TM)software were used to identify spatial and space-time clusters.In addition,the cases were characterized by sex,age,home situation(in a rural or urban area),and temporal tendency.Results:Acre reported an incidence rate of 12.4 cases per 10000 inhabitant-years in the study period,with the rates varied greatly(standard deviation of 21.8)among their 22 municipalities.One agglomeration of high risk and three of low risk were detected in space and space-time.Four of the five micro-regions of Acre presented a stationary temporal tendency.The profile of transmission varied according to the micro-region.Generally speaking,the disease occurred more often among young people,those of male gender,and those living in rural areas.Conclusions:Acre has stood out within the Brazilian national context due to its high rates of ACL incidence in the central region of the Acre Valley.The high rates in the micro-region of Brasileia are related to the disease’s intra/peridomiciliary occurrence,and it would seem that the municipality of Sena Madureira is approaching a transmission pattern similar to that of Brasileia.In other micro-regions,the profile of the disease’s transmission is mainly related to the forest/sylvatic cycle of ACL.展开更多
基金This study had financial support from CAPES(Coordination for the Improvement of Higher Education Personnel).
文摘Background:Acre has reported the highest incidence of American cutaneous leishmaniasis(ACL)in Brazil in recent years.The present study seeks to identify high and low risk agglomerations of ACL in space and space-time during the period from 2007 to 2013 in Acre,and also to characterize the occurrence of the disease in time and according to sociodemographic variables.Methods:This is an ecological study,the study population of which consisted of autochthonous ACL cases notified in the municipalities of Acre by an epidemiological surveillance system.Scan statistics of SaTScan^(TM)software were used to identify spatial and space-time clusters.In addition,the cases were characterized by sex,age,home situation(in a rural or urban area),and temporal tendency.Results:Acre reported an incidence rate of 12.4 cases per 10000 inhabitant-years in the study period,with the rates varied greatly(standard deviation of 21.8)among their 22 municipalities.One agglomeration of high risk and three of low risk were detected in space and space-time.Four of the five micro-regions of Acre presented a stationary temporal tendency.The profile of transmission varied according to the micro-region.Generally speaking,the disease occurred more often among young people,those of male gender,and those living in rural areas.Conclusions:Acre has stood out within the Brazilian national context due to its high rates of ACL incidence in the central region of the Acre Valley.The high rates in the micro-region of Brasileia are related to the disease’s intra/peridomiciliary occurrence,and it would seem that the municipality of Sena Madureira is approaching a transmission pattern similar to that of Brasileia.In other micro-regions,the profile of the disease’s transmission is mainly related to the forest/sylvatic cycle of ACL.
