Breast cancer is the most common cancer diagnosis worldwide,ac-counting for a quarter of new cancer diagnoses in women annually.In 2020,there were 2.3 million women newly-diagnosed with breast can-cer and 7.8 million ...Breast cancer is the most common cancer diagnosis worldwide,ac-counting for a quarter of new cancer diagnoses in women annually.In 2020,there were 2.3 million women newly-diagnosed with breast can-cer and 7.8 million women living with a diagnosis within the past 5 years,making breast cancer the world’s most prevalent cancer as well.1 It is the second leading cause of cancer death among women worldwide,and fifth in mortality among all cancers(men and women combined)with approximately 685,000 deaths in 2020.1 While the global burden of breast cancer is rising,it varies greatly between countries(Fig.1).In 2020,China had the largest number of breast cancer cases(18.4%of the global total),followed by the US with 11.8%of total breast cancer cases.展开更多
Non-Hodgkin lymphoma(NHL)contributes to significant cancer burden and mortality globally.In recent years,much insight into the causes of NHL has been gained by evaluating global differences through international colla...Non-Hodgkin lymphoma(NHL)contributes to significant cancer burden and mortality globally.In recent years,much insight into the causes of NHL has been gained by evaluating global differences through international collaboration and data pooling.NHL comprises different subtypes that are known to behave differently,exhibit different prognoses,and start in distinct cell types(B-cell,T-cell,and NK-cell,predominantly),and there is in-creasing evidence that NHL subtypes have different etiologies.Classification of NHL can be complex,with varying subtype frequencies,and is a consideration when evaluating geographic differences.Because of this,international pooling of well-executed epidemiologic studies has conferred power to evaluate NHL by subtype and confidence with minimal misclassification.Given the decreasing burden in some regions while cases rise in Asia,and espe-cially China,this report focuses on a review of the established etiology of NHL from the epidemiologic literature in recent decades,highlighting work from China.Topics covered include demographic patterns and genetic de-terminants including family history of NHL,as well as infection and immunosuppression,lifestyle,environment,and certain occupational exposures contributing to increased disease risk.展开更多
文摘Breast cancer is the most common cancer diagnosis worldwide,ac-counting for a quarter of new cancer diagnoses in women annually.In 2020,there were 2.3 million women newly-diagnosed with breast can-cer and 7.8 million women living with a diagnosis within the past 5 years,making breast cancer the world’s most prevalent cancer as well.1 It is the second leading cause of cancer death among women worldwide,and fifth in mortality among all cancers(men and women combined)with approximately 685,000 deaths in 2020.1 While the global burden of breast cancer is rising,it varies greatly between countries(Fig.1).In 2020,China had the largest number of breast cancer cases(18.4%of the global total),followed by the US with 11.8%of total breast cancer cases.
文摘Non-Hodgkin lymphoma(NHL)contributes to significant cancer burden and mortality globally.In recent years,much insight into the causes of NHL has been gained by evaluating global differences through international collaboration and data pooling.NHL comprises different subtypes that are known to behave differently,exhibit different prognoses,and start in distinct cell types(B-cell,T-cell,and NK-cell,predominantly),and there is in-creasing evidence that NHL subtypes have different etiologies.Classification of NHL can be complex,with varying subtype frequencies,and is a consideration when evaluating geographic differences.Because of this,international pooling of well-executed epidemiologic studies has conferred power to evaluate NHL by subtype and confidence with minimal misclassification.Given the decreasing burden in some regions while cases rise in Asia,and espe-cially China,this report focuses on a review of the established etiology of NHL from the epidemiologic literature in recent decades,highlighting work from China.Topics covered include demographic patterns and genetic de-terminants including family history of NHL,as well as infection and immunosuppression,lifestyle,environment,and certain occupational exposures contributing to increased disease risk.
