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含乙醇酸、水杨酸、辛酰水杨酸和烟酰胺的外用配方改善轻、中度痤疮症状的临床观察 被引量:5
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作者 李舒婷 何晓峰 +5 位作者 张中兴 Julie CRIBIER Sabina MERALLI-BALLOU andrew steel 鞠强 牛悦青 《临床皮肤科杂志》 CAS CSCD 北大核心 2022年第3期175-179,共5页
目的:评价含乙醇酸、水杨酸、辛酰水杨酸和烟酰胺的外用配方改善轻、中度痤疮临床症状的有效性和安全性。方法:招募66例轻、中度女性痤疮患者,按要求使用测试产品28 d后停用14 d,分别在使用前、使用7 d和28 d以及停用7 d和14 d后由皮肤... 目的:评价含乙醇酸、水杨酸、辛酰水杨酸和烟酰胺的外用配方改善轻、中度痤疮临床症状的有效性和安全性。方法:招募66例轻、中度女性痤疮患者,按要求使用测试产品28 d后停用14 d,分别在使用前、使用7 d和28 d以及停用7 d和14 d后由皮肤科医生进行痤疮皮损计数、痤疮炎症后红斑和色素沉着计数、毛孔可见度和肤色均匀度评级,拍摄面部标准照片并进行图像分析,并由患者完成自我评价问卷。结果:共有42例患者完成全部试验。与使用前相比,测试产品在使用后7 d和28 d能显著减少非炎性和炎性皮损数量,改善毛孔可见度和肤色均匀度,并且在停用后14 d内仍能维持效果。此外,测试产品对于肤色、红斑程度/面积及血流灌注等图像分析指标也有显著的改善作用。患者对测试产品耐受良好,表现出了较高的满意度和持续使用的意愿。结论:含乙醇酸、水杨酸、辛酰水杨酸和烟酰胺的外用配方对于改善轻、中度痤疮临床症状具有较好的有效性和安全性,减少皮损同时能减轻痤疮炎症后红斑和色素沉着并改善肤质和肤色。 展开更多
关键词 痤疮
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Experimental testing of low-energy rockfall catch fence meshes
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作者 Zhiwei Gao Hassan Al-Budairi andrew steel 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2018年第4期798-804,共7页
Flexible catch fences are widely used to protect infrastructure like railways, roads and buildings from rockfall damage. The wire meshes are the most critical components for catch fences as they dissipate most of the ... Flexible catch fences are widely used to protect infrastructure like railways, roads and buildings from rockfall damage. The wire meshes are the most critical components for catch fences as they dissipate most of the impact energy. Understanding their mechanical response is crucial for a catch fence design. This paper presents a new method for testing the wire meshes under rock impact. Wire meshes with different lengths can be used and the supporting cables can be readily installed in the tests. It is found that a smaller boulder causes more deformation localisation in the mesh. Longer mesh length makes the fence more flexible. Under the same impact condition, the longer mesh deforms more along the impact direction and shrinks more laterally. Supporting cables can reduce the lateral shrinkage of the mesh effectively. Most of the impact energy is dissipated by stretching of the wires.Wire breakage has not been observed. 展开更多
关键词 Rockfall catch fence Steel wire mesh Impact test Energy dissipation
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