To present the use of automated lamellar therapeutic keratoplasty (ALTK) for t he treatment of post-photorefractive keratectomy (PRK) corneal scarring and thi nning with significant residual myopia. Interventional cas...To present the use of automated lamellar therapeutic keratoplasty (ALTK) for t he treatment of post-photorefractive keratectomy (PRK) corneal scarring and thi nning with significant residual myopia. Interventional case report. A patient wi th high myopia of-12 diopters previously underwent PRK that resulted in corneal scarring, myopic regression, moderate loss of best-corrected visual acuity, a residual refractive error of -6.50/-1.00 ×.175 degrees, and a remaining corneal thickness of 300 μm. ALTK was first performed to remove the scar and to augment corneal thickness, and a subsequent laser-assisted in-situ keratomi leusis (LASIK) procedure was performed to correct the residual myopia. ALTK effe ctively removed the corneal scar and augmented the corneal thickness to 639 μm. LASIK effectively treated the residual myopia, resulting in an unaided visual a cuity of 20/25 and a stable refractive error of plano/-0.50 ×40 degrees. The A LTK interface remained clear throughout the follow-up period of 26 months. ALTK may be a reasonable alternative to conventional penetrating keratoplasty in the treatment of post-PRK corneal scarring and thinning, with a moderate loss of b est-corrected visual acuity, and LASIK can be subsequently performed to correct the residual refractive error and achieve an excellent refractive and visual ou tcome.展开更多
PURPOSE: To describe the use of an autologous serumfree derived cultivated conjunctival epithelial equivalent in the treatment of extensive recurrent viral papillomata. DESIGN: Interventional case report. METHODS: A 1...PURPOSE: To describe the use of an autologous serumfree derived cultivated conjunctival epithelial equivalent in the treatment of extensive recurrent viral papillomata. DESIGN: Interventional case report. METHODS: A 10- year-old child with extensive recurrent viral papillomata involving the superior and inferior tarsal, forniceal, and bulbar conjunctiva underwent surgical excision of all diseased areas and double freeze-thaw cryotherapy. Autologous serum-free cultivated conjunctival equivalents were used to reconstruct the ocular surface and conjunctival fornices. RESULTS: Almost complete epithelialization was achieved within 5 days postoperatively. A good cosmetic and functional result was obtained, and no recurrences or cicatricial complications developed during 12-month followup. CONCLUSION: Transplantation of autologous cultivated conjunctiva was effectively used in the reconstruction of the ocular surface after extensive excision of recurrent viral papillomata. This modality of treatment may be useful in the treatment of ocular surface disorders in which extensive conjunctival and fornix reconstruction is required.展开更多
文摘To present the use of automated lamellar therapeutic keratoplasty (ALTK) for t he treatment of post-photorefractive keratectomy (PRK) corneal scarring and thi nning with significant residual myopia. Interventional case report. A patient wi th high myopia of-12 diopters previously underwent PRK that resulted in corneal scarring, myopic regression, moderate loss of best-corrected visual acuity, a residual refractive error of -6.50/-1.00 ×.175 degrees, and a remaining corneal thickness of 300 μm. ALTK was first performed to remove the scar and to augment corneal thickness, and a subsequent laser-assisted in-situ keratomi leusis (LASIK) procedure was performed to correct the residual myopia. ALTK effe ctively removed the corneal scar and augmented the corneal thickness to 639 μm. LASIK effectively treated the residual myopia, resulting in an unaided visual a cuity of 20/25 and a stable refractive error of plano/-0.50 ×40 degrees. The A LTK interface remained clear throughout the follow-up period of 26 months. ALTK may be a reasonable alternative to conventional penetrating keratoplasty in the treatment of post-PRK corneal scarring and thinning, with a moderate loss of b est-corrected visual acuity, and LASIK can be subsequently performed to correct the residual refractive error and achieve an excellent refractive and visual ou tcome.
文摘PURPOSE: To describe the use of an autologous serumfree derived cultivated conjunctival epithelial equivalent in the treatment of extensive recurrent viral papillomata. DESIGN: Interventional case report. METHODS: A 10- year-old child with extensive recurrent viral papillomata involving the superior and inferior tarsal, forniceal, and bulbar conjunctiva underwent surgical excision of all diseased areas and double freeze-thaw cryotherapy. Autologous serum-free cultivated conjunctival equivalents were used to reconstruct the ocular surface and conjunctival fornices. RESULTS: Almost complete epithelialization was achieved within 5 days postoperatively. A good cosmetic and functional result was obtained, and no recurrences or cicatricial complications developed during 12-month followup. CONCLUSION: Transplantation of autologous cultivated conjunctiva was effectively used in the reconstruction of the ocular surface after extensive excision of recurrent viral papillomata. This modality of treatment may be useful in the treatment of ocular surface disorders in which extensive conjunctival and fornix reconstruction is required.
