A retrospective analysis of the factors associated with increased risk of readmission within 30 days after primary transurethral resection of bladder tumor

Background:Transurethral resection of bladder tumor(TURBT)is associated with perioperative morbidity of 5%to 10%,which can lead to unplanned readmissions.In this study,we aimed to identify the factors that lead to an increased risk of unplanned readmissions within 30 days of primary TURBT.Materials and methods:A retrospective study was conducted to identify patients who underwent primary TURBT at our institute from 2011 to 2019.Clinical and demographic factors,history of smoking,antiplatelet drugs intake,comorbidities,tumor size(<3 or>3 cm),multifocality,and histopathological type were abstracted.Patients who were readmitted were identified,and reasons for admission were recorded.Results:A total of 435 patients were identified.The median age of the patients was 66 years.From 378 male patients(86.9%),110(25.3%)and 37(8.5%)had a history of smoking and antiplatelet agents intake,respectively.In the cohort,166 patients(38.2%)were diabetic,239(54.9%)were hypertensive,72(16.6%)had chronic obstructive pulmonary disease,and 78(7.9%)had hypothyroidism.A total of 206 patients(47.4%)had a tumor>3 cm;multifocality was seen in 140(32.2%)patients,whereas muscle invasive tumors were present in 161 patients(37%).A total of 22 patients(5.06%)had readmissions within 30 days,with hematuria being the most common etiology.On univariate and multivariate analyses,a history of smoking(p=0.006 and p=0.008,respectively)or antiplatelet agents intake(p<0.001 and p<0.001,respectively)was significantly associated with increased unplanned readmission.Conclusions:Our study revealed smoking and antiplatelet agents intake as factors leading to an increased risk of unplanned readmissions.