Obsessive-compulsive disorder(OCD) is one of the most difficult additional diagnoses to manage in patients with bipolar disorder(BD) since the gold standard treatment for one disease(antidepressants for OCD) can worse...Obsessive-compulsive disorder(OCD) is one of the most difficult additional diagnoses to manage in patients with bipolar disorder(BD) since the gold standard treatment for one disease(antidepressants for OCD) can worsen the other. This case report describes the efficacy of aripiprazole augmentation as maintenance therapy in a young patient with comorbid BD-OCD. Our patient presented complete remission of affective and obsessivecompulsive symptoms with remarkable improvement in social and occupational functioning for 24 months.Adverse drug reactions were not severe enough to result in drug discontinuation. In consideration of the important nosological, clinical and therapeutic implications, future research efforts may lead to more grounded guidelines,which are greatly needed in patients with comorbid BDOCD.展开更多
To the editor:Apparent comorbidity between bipolar disorder（BD）and anxiety disorders is a common condition in psychiatry,[1,2]one of the most difficult to manage being the co-occurrence of BD and obsessive-compulsiv...To the editor:Apparent comorbidity between bipolar disorder（BD）and anxiety disorders is a common condition in psychiatry,[1,2]one of the most difficult to manage being the co-occurrence of BD and obsessive-compulsive disorder（OCD）.[3,4]In 1860 French psychiatrist BénédictAugustin Morel first described patients with symptoms typical of what is now considered comorbid BD and OCD.[5]A century later,when categorizing展开更多
文摘Obsessive-compulsive disorder(OCD) is one of the most difficult additional diagnoses to manage in patients with bipolar disorder(BD) since the gold standard treatment for one disease(antidepressants for OCD) can worsen the other. This case report describes the efficacy of aripiprazole augmentation as maintenance therapy in a young patient with comorbid BD-OCD. Our patient presented complete remission of affective and obsessivecompulsive symptoms with remarkable improvement in social and occupational functioning for 24 months.Adverse drug reactions were not severe enough to result in drug discontinuation. In consideration of the important nosological, clinical and therapeutic implications, future research efforts may lead to more grounded guidelines,which are greatly needed in patients with comorbid BDOCD.
文摘To the editor:Apparent comorbidity between bipolar disorder（BD）and anxiety disorders is a common condition in psychiatry,[1,2]one of the most difficult to manage being the co-occurrence of BD and obsessive-compulsive disorder（OCD）.[3,4]In 1860 French psychiatrist BénédictAugustin Morel first described patients with symptoms typical of what is now considered comorbid BD and OCD.[5]A century later,when categorizing
