The use of magnesium alloys,as a biodegradable medical device,is an interesting challenge for the biomaterials field.Its rapid degradation and the release of hydrogen,when exposed to biological fluids,are the main dra...The use of magnesium alloys,as a biodegradable medical device,is an interesting challenge for the biomaterials field.Its rapid degradation and the release of hydrogen,when exposed to biological fluids,are the main drawbacks for clinical applications.In this work,a coating made of polydopamine(PDOPA),is used as an intermediate layer to decrease the degradation rate of AZ31 magnesium alloy/polymeric coating system,when exposed to Hank’s solution.Experimental results highlighted:(i)the formation of a thin PDOPA layer,(ii)an increased adhesion in the organic coating/metallic substrate system,(iii)a decrease of two orders of magnitude of the corrosion rate when the PDOPA film is used together with an external organic coating,(iv)the efficacy in the use of PDODA due to the synergistic effect of both,physical and chemical,interactions between the PDOPA layer and the organic coating.展开更多
Magnesium alloys are candidates as biodegradable medical materials due to their biocompatibility and favorable mechanical properties.Unfortunately,the high corrosion rate in physiological media and the release of hydr...Magnesium alloys are candidates as biodegradable medical materials due to their biocompatibility and favorable mechanical properties.Unfortunately,the high corrosion rate in physiological media and the release of hydrogen,limit their widespread use in biomedical applications.In this work,an intermediate coating based on polydopamine(PDOPA),between Mg substrate and an organic coating,was used to decreasing the degradation rate of AZ31 magnesium alloy,during the long-term exposure in simulated body fluid.Electrochemical Impedance Spectroscopy measurements were carried out to study the corrosion resistance of samples.Results demonstrated that the PDOPA interlayer determined the reduction of the substrate degradation rate.The results were interpreted supposing a synergistic effect which occurred when PDOPA and the organic coating were used together.展开更多
Magnesium alloys are candidates to be used as biodegradable biomaterials for producing medical device.Their use is restricted due to the high degradation rate in physiological media.To contribute to solving this probl...Magnesium alloys are candidates to be used as biodegradable biomaterials for producing medical device.Their use is restricted due to the high degradation rate in physiological media.To contribute to solving this problem,a polydopamine(PDOPA)layer could be used to increase adhesion between the metallic substrate and external organic coating.In this paper,the corrosion behaviour of samples was investigated to determine their performance during the long-term exposure in simulated body fluid.Electrochemical methods including Open Circuit Potential(OCP)and Electrochemical Impedance Spectroscopy(EIS)were used to investigate the corrosion resistance of samples.The results demonstrated a decreasing of the substrate degradation rate when PDOPA was used as interlayer supposing a synergistic effect when it was used together with the organic coating.展开更多
文摘The use of magnesium alloys,as a biodegradable medical device,is an interesting challenge for the biomaterials field.Its rapid degradation and the release of hydrogen,when exposed to biological fluids,are the main drawbacks for clinical applications.In this work,a coating made of polydopamine(PDOPA),is used as an intermediate layer to decrease the degradation rate of AZ31 magnesium alloy/polymeric coating system,when exposed to Hank’s solution.Experimental results highlighted:(i)the formation of a thin PDOPA layer,(ii)an increased adhesion in the organic coating/metallic substrate system,(iii)a decrease of two orders of magnitude of the corrosion rate when the PDOPA film is used together with an external organic coating,(iv)the efficacy in the use of PDODA due to the synergistic effect of both,physical and chemical,interactions between the PDOPA layer and the organic coating.
文摘Magnesium alloys are candidates as biodegradable medical materials due to their biocompatibility and favorable mechanical properties.Unfortunately,the high corrosion rate in physiological media and the release of hydrogen,limit their widespread use in biomedical applications.In this work,an intermediate coating based on polydopamine(PDOPA),between Mg substrate and an organic coating,was used to decreasing the degradation rate of AZ31 magnesium alloy,during the long-term exposure in simulated body fluid.Electrochemical Impedance Spectroscopy measurements were carried out to study the corrosion resistance of samples.Results demonstrated that the PDOPA interlayer determined the reduction of the substrate degradation rate.The results were interpreted supposing a synergistic effect which occurred when PDOPA and the organic coating were used together.
文摘Magnesium alloys are candidates to be used as biodegradable biomaterials for producing medical device.Their use is restricted due to the high degradation rate in physiological media.To contribute to solving this problem,a polydopamine(PDOPA)layer could be used to increase adhesion between the metallic substrate and external organic coating.In this paper,the corrosion behaviour of samples was investigated to determine their performance during the long-term exposure in simulated body fluid.Electrochemical methods including Open Circuit Potential(OCP)and Electrochemical Impedance Spectroscopy(EIS)were used to investigate the corrosion resistance of samples.The results demonstrated a decreasing of the substrate degradation rate when PDOPA was used as interlayer supposing a synergistic effect when it was used together with the organic coating.
