Increasing dietary fiber intake in terms of kiwifruit improves constipation in Chinese patients

瞄准：如果以弥猴桃，增加的饮食的纤维在中国便秘的病人是有效的，调查。方法：33 个便秘的病人和 20 个健康志愿者每天为弥猴桃的 4-wk 治疗被招募两次。反应在 wk 1-4 期间被定义为完全的自发的碗的增加，运动(CSBM )】= 1/wk。第二等的功效在肠习惯和便秘的 wk 1-4，单个症状和分数期间包括了反应。回答与基线 run-in 时期相比。结肠的运输时间和肛门直肠的测压法在治疗前后被执行。结果：应答者率在便秘的组是 54.5% 。吝啬的 CSBM 增加了术后疗法(2.2 +/- 2.6 对 4.4 +/- 4.6， P = 0.013 ) 。也在为便秘的麻烦海角的分数有改进(P = 0.02 ) ，并且肠习惯的满足(P = 0.001 ) ，并且在使用的 laxative 的天内减少了(P = 0.003 ) 。也在运输时间有改进(P = 0.003 ) 并且直肠的感觉(P 【 0.05 ) 。然而，在健康题目在肠症状或肛门直肠的生理学没有变化。结论：增加饮食的纤维吸入在在中国人口减轻长期的便秘是有效的。

Increasing prevalence of advanced colonic polyps in young patients undergoing colonoscopy in a referral academic hospital in Hong Kong

AIM: To investigate the distribution and frequency of advanced polyps over eight years. METHODS: 6424 colonoscopies were reviewed during the study period 1998 to 2005. The study period was subdivided into period Ⅰ: 1998 to 2001 and period Ⅱ: 2002-2005. RESULTS: 1856 polyps (33% advanced polyps) and 328 CRCs were detected. The mean ages of the patients with advanced polyps and cancer were 69.2 ± 12.0 and 71.6 ± 13.8 years, respectively. Advanced polyps were mainly left sided (59.5%). Advanced polyps were found in patients ≤ 60 years from 17.7% in periodⅠto 26.3% in period Ⅱ (P < 0.05), especially in male subjects ≤ 60 years (21.6% vs 31.6%, P < 0.05). Advanced tubulovillous polyps rose from 21.5% in period Ⅰto 29.5% in period Ⅱ (P < 0.05). Whereas cancers in male patients ≤ 60 years were similar in both periods: 23.2% vs 16.5% (P > 0.05). CONCLUSION: Advanced polyps increased significantly in the younger male group in the most recent period and there seems to be a shift towards a proximal location.

E-cadherin in gastric cancer

Cadherin 是一个粘附分子和调停钙的膜 glycoproteins 的一个总科。E-cadherin 是连接到 catenins 形成细胞骨架的班 E-cadherin 的原型。最近的证据显示出那 E-cadherin 不仅充当粘合剂，而且在生长开发和致癌作用起重要作用。它最近被看作了侵略以及生长压制或基因。这评论在胃的癌症在 E-cadherin 和它的角色上总结最近的发现。特别地，包括它有 Helicobacter pylori 和临床的应用的关系，我们在胃的癌症的 E-cadherin 上的工作详细被描述。