Abstract Previous studies have suggested that cortical functional reorganization is associated with motor recovery after stroke and that normal afferent sensory information is very important in that process. In this s...Abstract Previous studies have suggested that cortical functional reorganization is associated with motor recovery after stroke and that normal afferent sensory information is very important in that process. In this study, we selected patients who had a stroke in or under the thalamus, with potentially impaired afferent sensory information and analyzed the differences between these patients and healthy controls at three levels： brain regions, the functional con- nectivity between brain areas, and the whole-brain func- tional network. Compared with healthy controls, regionalhomogeneities in the left middle temporal gyrus decreased and functional connectivity between the left middle tem- poral gyrus and the stroke area increased in the patients. However, there was no significant change in the whole- brain functional network. By focusing on stroke located in or under the thalamus, our study contributes to wider inquiries into understanding and treating stroke.展开更多
基金supported by grants from the National Natural Science Foundation of China(31230032,31171083, and 31471071)Fundamental Research Funds for the Central Universities of China(WK2070000033)+1 种基金the Natural Science Foundation of Anhui Province,China(1208085MH179)Hefei Science Center,CAS "User with Potential"(2015HSC-UP017)
文摘Abstract Previous studies have suggested that cortical functional reorganization is associated with motor recovery after stroke and that normal afferent sensory information is very important in that process. In this study, we selected patients who had a stroke in or under the thalamus, with potentially impaired afferent sensory information and analyzed the differences between these patients and healthy controls at three levels： brain regions, the functional con- nectivity between brain areas, and the whole-brain func- tional network. Compared with healthy controls, regionalhomogeneities in the left middle temporal gyrus decreased and functional connectivity between the left middle tem- poral gyrus and the stroke area increased in the patients. However, there was no significant change in the whole- brain functional network. By focusing on stroke located in or under the thalamus, our study contributes to wider inquiries into understanding and treating stroke.
