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Beyond the joint: Subclinical atherosclerosis in rheumatoid arthritis 被引量:2
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作者 Antongiulio Scarno Fabio Massimo Perrotta +4 位作者 Francesca Cardini Alessia Carboni Gianmarco Annibali Ennio Lubrano antonio spadaro 《World Journal of Orthopedics》 2014年第3期328-335,共8页
Rheumatoid arthritis is a chronic autoimmune inflammatory disease associated with increased cardiovascular risk and higher mortality in respect to general population.Beyond joint disease,inflammation is the major dete... Rheumatoid arthritis is a chronic autoimmune inflammatory disease associated with increased cardiovascular risk and higher mortality in respect to general population.Beyond joint disease,inflammation is the major determinant of accelerated atherosclerosis observed in rheumatoid arthritis.We review the relationship between inflammation,atherosclerosis and cardiovascular risk in rheumatoid arthritis,focusing on the assessment of subclinical atherosclerosis by functional and morphological methods.These tools include flow mediated dilatation,carotid intima-media thickness,ankle/brachial index,coronary calcium content,pulse wave analysis and serum biomarker of subclinical atherosclerosis. 展开更多
关键词 ATHEROSCLEROSIS RHEUMATOID ARTHRITIS Flow mediated dilatiation Intima-media thickness INFLAMMATION
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