Aging is a leading risk factor for pneumonia and subsequent comorbidities,including chronic pulmonary diseases.1 The underlying causes of age-related susceptibility to pneumonia-related morbidity and mortality are com...Aging is a leading risk factor for pneumonia and subsequent comorbidities,including chronic pulmonary diseases.1 The underlying causes of age-related susceptibility to pneumonia-related morbidity and mortality are complex and poorly understood.While aging has been associated with many changes in diverse immune compartments,if and how aging affects resident immune cells in the lung have not been examined.展开更多
基金supported by NIH grants including R01-AI115053,R35-HL135756,and R33-HL137081 to J.P.M.
文摘Aging is a leading risk factor for pneumonia and subsequent comorbidities,including chronic pulmonary diseases.1 The underlying causes of age-related susceptibility to pneumonia-related morbidity and mortality are complex and poorly understood.While aging has been associated with many changes in diverse immune compartments,if and how aging affects resident immune cells in the lung have not been examined.