Impact of task-oriented training based on acupuncture rehabilitation on upper extremity function and quality of life of patients with early stroke

BACKGROUND Eighty percent of stroke patients develop upper limb dysfunction,especially hand dysfunction,which has a very slow recovery,resulting in economic burden to families and society.AIM To investigate the impact of task-oriented training based on acupuncture therapy on upper extremity function in patients with early stroke.METHODS Patients with early stroke hemiplegia who visited our hospital between January 2021 and October 2022 were divided into a control group and an observation group,each with 50 cases.The control group underwent head acupuncture plus routine upper limb rehabilitation training(acupuncture therapy).In addition to acupuncture and rehabilitation,the observation group underwent upper limb task-oriented training(30 min).Each group underwent treatment 5 d/wk for 4 wk.Upper extremity function was assessed in both groups using the Fugl-Meyer Assessment-Upper Extremity(FMA-UE),Wolf Motor Function Rating Scale(WMFT),modified Barthel Index(MBI),and Canadian Occupational Performance Measure(COPM).Quality of life was evaluated using the Short-Form 36-Item Health Survey(SF-36).Clinical efficacy of the interventions was also evaluated.RESULTS Before intervention,no significant differences were observed in the FMA-UE,MBI,and WMFT scores between the two groups(P>0.05).After intervention,the FMA-UE,WMFT,MBI,COPM-Functional Mobility and Satisfaction,and SF-36 scores increased in both groups(P<0.05),with even higher scores in the observation group(P<0.05).The observation group also obtained a higher total effective rate than the control group(P<0.05).CONCLUSION Task-oriented training based on acupuncture rehabilitation significantly enhanced upper extremity mobility,quality of life,and clinical efficacy in patients with early stroke.

Effect of lens constants optimization on the accuracy of intraocular lens power calculation formulas for highly myopic eyes

AIM: To evaluate the effect of different lens constant optimization methods on the accuracy of intraocular lens(IOL) power calculation formulas for highly myopic eyes.METHODS: This study comprised 108 eyes of 94 consecutive patients with axial length(AL) over 26 mm undergoing phacoemulsification and implantation of a Rayner(Hove, UK) 920H IOL. Formulas were evaluated using the following lens constants: manufacturer’s lens constant, User Group for Laser Interference Biometry(ULIB) constant, and optimized constant for long eyes. Results were compared with Barrett Universal II formula, original Wang-Koch AL adjustment method, and modified Wang-Koch AL adjustment method. The outcomes assessed were mean absolute error(MAE) and percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 diopter(D). The nonparametric method, Friedman test, was used to compare MAE performance among constants.RESULTS: Optimized constants could significantly reduce the MAE of SRK/T, Hoffer Q, and Holladay 1 formulas compared with manufacturer’s lens constant, whereas the percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 D had no statistically significant differences. Optimized lens constant for long eyes alone showed non-significant refractive advantages over the ULIB constant. Barrett Universal II formula and formulas with AL adjustment showed significantly higher accuracy in highly myopic eyes(P<0.001). CONCLUSION: Lens constant optimization for the subset of long eyes reduces the refractive error only to a limited extent for highly myopic eyes.

Modeling and small-signal stability analysis of doubly-fed induction generator integrated system

Owing to their stability,doubly-fed induction generator(DFIG)integrated systems have gained considerable interest and are the most widely implemented type of wind turbines and due to the increasing escalation of the wind generation penetration rate in power systems.In this study,we investigate a DFIG integrated system comprising four modules:(1)a wind turbine that considers the maximum power point tracking and pitch-angle control,(2)induction generator,(3)rotor/grid-side converter with the corresponding control strategy,and(4)AC power grid.The detailed small-signal modeling of the entire system is performed by linearizing the dynamic characteristic equation at the steady-state value.Furthermore,a dichotomy method is proposed based on the maximum eigenvalue real part function to obtain the critical value of the parameters.Root-locus analysis is employed to analyze the impact of changes in the phase-locked loop,short-circuit ratio,and blade inertia on the system stability.Lastly,the accuracy of the small-signal model and the real and imaginary parts of the calculated dominant poles in the theoretical analysis are verified using PSCAD/EMTDC.

Synthesis and Performance Evaluation of Organic Bentonite Modifier Dimethyldistearylammonium Bromide (DODMAB)

Dimethyldistearylammonium Bromide (DODMAB) is a bentonite modifier with good performance. In this experiment, 1-Bromooctadecane is the raw material, and completes tertiary amination and quaternization successively by changing the condition of experiment. The result is that the productivity can achieve 78.94% in the synthesis of DODMAB. It has been used in the experiment of bentonite modification and achieves good results;compared with using trimethylstearylammonium bromide as the organic modifier, the synthetic organic bentonite has better performance than the common organic modifier when used in the oil base drilling fluid of oilfield operation.

Hot-electron deposition and implosion mechanisms within electron shock ignition

A hot-electron driven scheme can be more effective than a laser-driven scheme within suitable hot-electron energy and target density. In our one-dimensional (1D) radiation hydrodynamic simulations, 20× pressure enhancement was achieved when the ignitor laser spike was replaced with a 60-keV hot-electron spike in a shock ignition target designed for the National Ignition Facility (NIF), which can lead to greater shell velocity. Higher hot-spot pressure at the deceleration phase was obtained owing to the greater shell velocity. More cold shell material is ablated into the hot spot, and it benefits the increases of the hot-spot pressure. Higher gain and a wider ignition window can be observed in the hot-electron-driven shock ignition.

Analytical solution of crystal diffraction intensity

Plasma density and temperature can be diagnosed by x-ray line emission measurement with crystal,and bent crystals such as von Hamos and Hall structures are proposed to improve the diffraction brightness.In this study,a straightforward solution for the focusing schemes of flat and bent crystals is provided.Simulations with XOP code are performed to validate the analytical model,and good agreements are achieved.The von Hamos or multi-cone crystal can lead to several hundred times intensity enhancements for a 200μm plasma source.This model benefits the applications of the focusing bent crystals.

The Synthesis and Evaluation of Hydrophobic Association Thickener

The paper provides a new hydrophobic association polymer fracturing fluid gelatinizer. The hydrophobic association which is the synthesis of three component copolymer complexes, is compounded by micellar copolymerization method. The hydrophobic association is got together through hydrophilic monomer acrylamide monomer N,N-vinyl pyrrolidone monomer with a rigid group N, and hydrophobic monomer N,N-2 dodecyl acrylamide etc. three monomers with sodium dodecyl sulfate as the emulsifier in micellar solution.

The Synthesis and Evaluation of a Novel Inhibitor DN for Carbon Dioxide Corrosion

During the oil and gas wells exploitation and transportation, carbon dioxide corrosion is one of main reasons for the corrosion of metallic materials. So the methods of preventing and reducing carbon dioxide corrosion have become a widely focused problem. The foreign and domestic practices and experiences show that as an economic, effective and versatile metal corrosion control method, corrosion inhibitor protection technology is suitable for application in oil and gas transportation system. This paper, through the indoor experiment with benzyl chloride, using quinoline as raw materials, synthesizes a kind of quinoline quaternary ammonium salt. The obtained product benzyl chloride quinoline compounded with OP-10 and ethanol to get a novel inhibitor DN for carbon dioxide corrosion, and to evaluate its performance.

Anti-Inflammatory Glycosaminoglycan Oligosaccharides from Colwellia psychrerythraea 34H Capsule:Synthesis and Biological Evaluation

Capsular polysaccharides(CPS)of Colwellia psychrerythraea 34H consist of linear tetrasaccharides repeating units in a glycosaminoglycan-like fashion.Their biological function is likely involved in the cold adaptation of microbial organisms.The low availability of these glycosaminoglycan structures greatly limits the study of their functions and biological activities.Here,an efficient semisynthetic strategy for CPS tetrasaccharide derivatives is achieved by using disaccharide units degraded from hyaluronic acids.This new synthetic process is suitable for largescale preparation,and several rare tetrasaccharide derivatives containing GalA-GalNAc were readily obtained in high yields.Biological evaluation of their anti-inflammatory effects demonstrated that these CPS tetrasaccharides effectively attenuated the lipopolysaccharide-induced sepsis and acute lung injury by decreasing macrophage infiltration and secretion of microphage-related cytokines in mice.All these results suggest that this new type of CPS tetrasaccharide can be developed as an anti-inflammation agent.

Adhesive chitosan-based hydrogel assisted with photothermal antibacterial property to prompt mice infected skin wound healing

Bacterial infection of wounds is an escalating medical problem,issuing threats to both global public health and personal health.Photothermal antibacterial technology as a novel sterilization strategy has outstanding sterilization efficiency,high safety and low risk of emergence of drug-resistant bacteria.By combining inherent antibacterial activity and light-assisted antibacterial treatment,developing novel multifunctional dressings with synergistic high-efficiency antibacterial effects and also promoting wound healing possesses attractive advantages in the field of treating bacterial wound infections in clinical care.Herein,a multifunctional hydrogel formed by in situ photo-cross linking was designed and prepared by first grafting methacrylic anhydride as a photosensitizer onto chitosan,and then introducing oxidatively synthesized polydopamine(PDA).The physicochemical characterizations of the synthesized hydrogels demonstrated their tunability certainly associated with PDA concentration,including pore size,water swelling,rheological properties and in vitro degradability.In addition,the composite hydrogels exhibited good adhesion,anti-oxidation and photothermal properties due to the existence of PDA.Within 10min upon exposure to 808 nm near-infrared(NIR)light irradiation,this hydrogel system displayed outstanding antibacterial activity against Staphylococcus aureus with almost 100%killing efficiency,of which rapid efficient sterilization plays a significant role in wound healing.Moreover,the hydrogel is capable of cytocompatibility and has low toxicity to murine fibroblasts(L929 and NIH/3T3).In the full-thickness wound defect infection model in mice,the wound closure ratio,inflammatory response,fibroblasts,neovascularization and epithelialization were measured.Animal experiments also reveal that the hydrogel assisted with NIR laser irradiation can inhibit effectively infection at an early stage and accelerate the wound healing process.In summary,this novel multifunctional injectable hydrogel exhibits excellent swelling capacity,bio-adhesion,antioxidant property,photothermal activity,efficient antibacterial property and facilitates skin healing,which has great promising application as a medical dressing biomaterial in infected wound carefields.

Feasibility of feeding cadmium accumulator maize(Zea mays L.)to beef cattle:Discovering a strategy for eliminating phytoremediation residues

Eco-friendly and efficient strategies for eliminating cadmium (Cd) phytoremediation plant residues are needed. The present study investigated the feasibility of feeding Cd accumulator maize to beef cattle. In total, 20 cattle at 6 months of age were selected and randomly allocated into two groups fed with 85.82%(fresh basis) Cd accumulator maize (CAM) or normal maize (control [Con]) silage diets for 107 d. Feeding CAM did not affect the body weight (P=0.24), while it decreased feed intake and increased feed efficiency of beef cattle (P <0.01). Feeding CAM increased serum concentrations of immunoglobulin A and G, complement 3 and 4, blood urea nitrogen, and low-density lipoprotein cholesterol, decreased serum concentrations of interleukin-6 and lipopolysaccharide (P <0.05), and caused wider lumens in the renal tubules. The Cd residue in meat was 7μg/kg beyond the restriction for human food. In the muscle, the unsaturated fatty acids (t11C18:1 and C20:4), Lys, Arg, Pro, and Cys were decreased, while the saturated fatty acids (C10:0, C12:0, and C17:0) and Leu were increased (P <0.05). Therefore, at the current feeding level, phytoremediation maize increased the feed efficiency of beef cattle, but did present risks to cattle health and production safety, and decreased the meat nutrition and flavor. Further research must be performed to determine whether a lower proper dose of phytoremediation maize and an appropriate feeding period may be possible to ensure no risk to cattle health and the supply of safe meat for humans.

Current research progress of photopolymerized hydrogels in tissue engineering

Owing to the special fo rmation of photopolymerized hydrogels,they can effectively control the formation of hydrogels in space and time.Moreover,the photopolymerized hydrogels have mild formation conditions and biocompatibility;therefore,they can be widely used in tissue engineering.With the development and application of manufacturing technology,photopolymerized hydrogels can be widely used in cell encapsulation,scaffold materials,and other tissue engineering fields through more elaborate manufacturing methods.This review covers the types of photoinitiators,manu facturing technologies for photopolymerized hydrogels as well as the materials used,and a summary of the applications of photopolymerized hydrogels in tissue engineering.

Designing a toroidal crystal for monochromatic X-ray imaging of a laser-produced He-like plasma

In this study,a toroidal quartz(2023)crystal is designed for monochromatic X-ray imaging at 72.3◦.The designed crystal produces excellent images of a laser-produced plasma emitting He-like Ti X-rays at 4.75 keV.Based on the simulations,the imaging resolutions of the spherical and toroidal crystals in the sagittal direction are found to be 15 and 5μm,respectively.Moreover,the simulation results show that a higher resolution image of the source can be obtained by using a toroidal crystal.An X-ray backlight imaging experiment is conducted using 4.75 keV He-like Ti X-rays,a 3×3 metal grid,an imaging plate and a toroidal quartz crystal with a lattice constant of 2d=0.2749 nm.The meridional and sagittal radii of the toroidalα-quartz crystal are 295.6 and 268.5 mm,respectively.A highly resolved image of the microgrid,with a spatial resolution of 10μm,is obtained in the experiment.By using similar toroidal crystal designs,the application of a spatially resolved spectrometer with high-resolution X-ray imaging ability is capable of providing imaging data with the same magnification ratio in the sagittal and meridional planes.

Improvement of Kdo’s efficient large-scale chemical synthesis method

Kdo residues are widely distributed in bacteria.They are components of bacterial lipopolysaccharide(LPS)and capsular polysaccharides,which can be recognized by the human adaptive immune system,and have great potential for developing new sugar chips and antibacterial vaccines.By improving the existing methods,we optimized the Kdo chemical synthesis method,which was able to efficiently synthesize Kdo monosaccharides with high purity,laying a foundation for the construction of subsequent compound libraries.Kdo acylation can easily form 1,5-lactones and reduce the efficiency of synthesis.By changing the synthesis sequence,we avoided the formation of Kdo 1,5-lactones,improved the synthesis efficiency of Kdo glycals,and provided a new strategy for derivatization.