Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In...Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon plasma.The triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.展开更多
Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive tumor.The high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells arou...Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive tumor.The high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells around GBM,which avert the entry of chemotherapeutic drugs into the tumormass.Objective:Recently,several researchers have designed novel nanocarrier systems like liposomes,dendrimers,metallic nanoparticles,nanodiamonds,and nanorobot approaches,allowing drugs to infiltrate the BBB more efficiently,opening up innovative avenues to prevail over therapy problems and radiation therapy.Methods:Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases,for example,PubMed,Science Direct,Google Scholar,and others,using specific keyword combinations,including“glioblastoma,”“brain tumor,”“nanocarriers,”and several others.Conclusion:This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM management.Elucidation of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.展开更多
The rivers draining from the Himalayan range distribute enormous amount of fresh water to the people living in downstream regions.Trace metals flowed with river water can lead to serious impact on ecological system an...The rivers draining from the Himalayan range distribute enormous amount of fresh water to the people living in downstream regions.Trace metals flowed with river water can lead to serious impact on ecological system and human health.Nevertheless,the documentation on trace elements of Himalayan rivers is inadequately documented.The current study deals with the spatial and temporal variability of the major and trace elements of Ganga river water in epirhithron,metarhithron and hyporhithron zone belonging to Himalayan segment.Water samples from nineteen monitoring locations were collected in pre-monsoon(May-June),monsoon(AugustSeptember)and post-monsoon(December)seasons and subjected to be assessed for 20 elements(Ag,Al,Ba,Cd,Ca,Cr,Cu,Fe,Ga,K,Mn,Mg,Na,Ni,Pb,Sr,Th,U,Zn,and Zr)using ICP-OES(Inductively Coupled Plasma-Optical Emission Spectrometer).Different water pollution indexes such as HPI(Heavy Metal Pollution Index),MI(Metal Index)and PI(Pollution Index)were used to describe current water quality status at each monitoring station under particular classified ecological zone.The studied stations in hyporhithron zone had the value of Metal Index(MI>1),indicating threshold of warning.Further,the highest values of HPI in hyporhithron zone correspond to poor water quality status.Sites with poor water quality were also found to be contaminated as per the Pollution Index(PI),exhibiting high concentrations for element(Fe).However,the epirhithron and metarhithron zone in Himalayan segment showed excellent water quality mainly contributed from natural sources.Cluster Analysis(CA)and Principal Component Analysis(PCA)were applied to identify the main influential sources for Ganga river water pollution.The Kriging interpolation method was also applied to prepare spatial distribution map of computed indexes(HPI,MI,and PI).With the help of index of local Moran’s I(LMI),identified spatial clusters and spatial outliers revealed the elevated concentration of most elements in hyporhithron zone.The dataset presented in this study would be convenient for government officials in developing more effective management policies and necessary steps to check and monitor the Ganga river water quality.It was also suggested that further investigations in terms of trace elemental sources and their role in self-purification properties of Ganga water can be addressed in future.展开更多
In recent times the fixed point results in partially ordered metric spaces has greatly developed. In this paper we prove common fixed point results for multivalued and singlevalued mappings in partially ordered metric...In recent times the fixed point results in partially ordered metric spaces has greatly developed. In this paper we prove common fixed point results for multivalued and singlevalued mappings in partially ordered metric space. Our theorems generalized the theorem in [1] and extends the many more recent results in such spaces.展开更多
The design details and performance characterization results of a newly developed plasma focus based compact and portable system(0.5 m×0.5 m×1.2 m,weighing≈100 kg)that produces an average neutron yield of^2&...The design details and performance characterization results of a newly developed plasma focus based compact and portable system(0.5 m×0.5 m×1.2 m,weighing≈100 kg)that produces an average neutron yield of^2×10^8 neutrons/shot(of fast D-D neutrons with typical energy^2.45 Me V)at^1.8 k J energy discharge are reported.From the detailed analysis of the experimental characterization and simulation results of this system,it has been conclusively revealed that specifically in plasma focus devices with larger static inductance:(i)pinch current is a reliable and more valid neutron yield scaling parameter than peak current,(ii)the ratio of pinch/peak current improves as static inductance of the system reduces,(iii)the benign role of the higher static/pinch inductance ratio enables the supply of inductively stored energy in densely pinched plasma with a larger time constant and it is well depicted by the extended dip observed in the discharge current trace,(iv)there is the need to redefine existing index values of the pinch(Ipinch^4.7)and peak(Ipeak^3.9)currents in neutron yield scaling equations to higher values.展开更多
In view of the wide use of plants as test systems theeffects of acute and chronic exposure were comparedon seeds of Pisum sativum and in meristematic cellsof Allium sativum root tips.The two salts comparedwere zirconi...In view of the wide use of plants as test systems theeffects of acute and chronic exposure were comparedon seeds of Pisum sativum and in meristematic cellsof Allium sativum root tips.The two salts comparedwere zirconium oxychloride and known to be ubiquitousin plant systems and thallium acetate known for toxiceffects in high doses.Seeds were soaked in展开更多
The effect of acute and chronic exposure to toxicmetals like CsCl and CoCl<sub>2</sub> on chromosomes and celldivision was studied in seeds of Trigonellafoenum graecum and root meristems of Alliumsativum.1...The effect of acute and chronic exposure to toxicmetals like CsCl and CoCl<sub>2</sub> on chromosomes and celldivision was studied in seeds of Trigonellafoenum graecum and root meristems of Alliumsativum.10,000,1000 & 100 ppm of CsCl and 1%,展开更多
The action of metals on living organisms has to bestudied as mixtures since exposure is seldom to asingle metal.The interaction between metals mayaffect the degree of action on enzymes.
Electromagnetic forming is a high-speed forming technology by which hollow profiles can be compressed or expanded. It is done with a pulsed magnetic field to apply Lorentz’ forces at electrically conductive material....Electromagnetic forming is a high-speed forming technology by which hollow profiles can be compressed or expanded. It is done with a pulsed magnetic field to apply Lorentz’ forces at electrically conductive material. Electromagnetic hollow tube expansion is limited by the fragmentation tendency. This work attempts to use a combination of analytical and computational approach to compute the net tangential stress during tube expansion. A simplified analytical framework to estimate the temporal evolution of plastic stresses present in aluminium alloy AA5052 at low and high applied magnetic pressures is developed based upon dynamic imaging. The time resolved images captured using current synchronised high speed camera record the overall dimensional changes of the tube that is validated by multi-physics simulation of expansion process. Imaging of hollow tube expansions at two selected peak currents has been carried out at various current levels in the range 76 - 160 kA. The direct visualisation of the increase in the tube diameter at two current levels provided a comparison of the developing net tangential stresses in the hollow tube during the undamaged and fragmented expansion. Imaging of tube expansion also facilitates the estimation of the strain rate experienced by the tube and was in the range of ~1700 s<sup>-1</sup> to ~1200 s<sup>-1</sup>. The propensity of fragmentation was found to be due to the level and duration of generated tangential stresses above the yield stress during expansion of the aluminium tubes. Presented study provides a mean of exploiting the enhanced formability of aluminium alloys using electromagnetic forming.展开更多
The composite materials based on nanopowder dispersed liquid crystals are important both from fundamental research and device applications due to their unique properties such as improvement in various properties like ...The composite materials based on nanopowder dispersed liquid crystals are important both from fundamental research and device applications due to their unique properties such as improvement in various properties like electrical,optical,thermal,energy storage and spontaneous polarization etc.The proper selection of nanoparticle and its size which to be dispersed in particular liquid crystals is very important for a particular application.In the present study,a ferroelectric nanopowder of Barium Titanate(BaTiO3)was dispersed in cholesteric liquid crystal and the same was confirmed by Fourier Transform Infrared(FTIR)Spectroscopy.The various acoustical properties like ultrasonic velocity,density,Adiabatic Compressibility,Rao Constant,Wada Constant and Acoustic Impedance were investigated by ultrasonic interferometer at room temperature at fixed frequency.The dielectric constant was determined by Precision Impedance Analyzer.In addition to these investigations,particle size and surface area were also measured.Our investigation shows enhanced in dielectric and acoustical properties which may be useful for device applications extensively in microelectronics,low cost-photovoltaic devices,and custom-shaped containers possibly applied as a coating.展开更多
The ubiquitous sameness of urban greenways prompts questions on generative design grammar and syntax, whether creative, critical rethinking at that level might be lacking. However the design syntax of urban greenways ...The ubiquitous sameness of urban greenways prompts questions on generative design grammar and syntax, whether creative, critical rethinking at that level might be lacking. However the design syntax of urban greenways is not explicitly discussed thus leaving a critical gap in knowledge. This paper begins tackling the larger question by acting on the fundamental subset of it, by operationatizing the design syntax of urban greenways. This is done through mathematics-based graph studies to analyze patterns and shapes, photography based thermal, material and morphology studies, and section analyses to make imagery-derived deductions on the design syntax. Recommendation on approaches to diversify and enrich the design syntax includes a more direct reference from ecosystem science theories such for siting and planning the urban greenways at macro- to meso-scale, a mixed-method approach, combining mathe- matics, photography and drawings based frames for analyses at meso- to micro-scale, and a turtle view scale for designing at meso- to micro-scale, with an emphasis on latter.展开更多
基金supported by Bhabha Atomic Research Centre, Department of Atomic Energy, Government of IndiaDepartment of Atomic Energy, Government of India for financial assistance under DAE Doctoral Fellowship Scheme-2018。
文摘Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon plasma.The triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.
文摘Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive tumor.The high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells around GBM,which avert the entry of chemotherapeutic drugs into the tumormass.Objective:Recently,several researchers have designed novel nanocarrier systems like liposomes,dendrimers,metallic nanoparticles,nanodiamonds,and nanorobot approaches,allowing drugs to infiltrate the BBB more efficiently,opening up innovative avenues to prevail over therapy problems and radiation therapy.Methods:Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases,for example,PubMed,Science Direct,Google Scholar,and others,using specific keyword combinations,including“glioblastoma,”“brain tumor,”“nanocarriers,”and several others.Conclusion:This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM management.Elucidation of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.
基金the Doon University,Dehradun,India,for the financial support to carry out the research work。
文摘The rivers draining from the Himalayan range distribute enormous amount of fresh water to the people living in downstream regions.Trace metals flowed with river water can lead to serious impact on ecological system and human health.Nevertheless,the documentation on trace elements of Himalayan rivers is inadequately documented.The current study deals with the spatial and temporal variability of the major and trace elements of Ganga river water in epirhithron,metarhithron and hyporhithron zone belonging to Himalayan segment.Water samples from nineteen monitoring locations were collected in pre-monsoon(May-June),monsoon(AugustSeptember)and post-monsoon(December)seasons and subjected to be assessed for 20 elements(Ag,Al,Ba,Cd,Ca,Cr,Cu,Fe,Ga,K,Mn,Mg,Na,Ni,Pb,Sr,Th,U,Zn,and Zr)using ICP-OES(Inductively Coupled Plasma-Optical Emission Spectrometer).Different water pollution indexes such as HPI(Heavy Metal Pollution Index),MI(Metal Index)and PI(Pollution Index)were used to describe current water quality status at each monitoring station under particular classified ecological zone.The studied stations in hyporhithron zone had the value of Metal Index(MI>1),indicating threshold of warning.Further,the highest values of HPI in hyporhithron zone correspond to poor water quality status.Sites with poor water quality were also found to be contaminated as per the Pollution Index(PI),exhibiting high concentrations for element(Fe).However,the epirhithron and metarhithron zone in Himalayan segment showed excellent water quality mainly contributed from natural sources.Cluster Analysis(CA)and Principal Component Analysis(PCA)were applied to identify the main influential sources for Ganga river water pollution.The Kriging interpolation method was also applied to prepare spatial distribution map of computed indexes(HPI,MI,and PI).With the help of index of local Moran’s I(LMI),identified spatial clusters and spatial outliers revealed the elevated concentration of most elements in hyporhithron zone.The dataset presented in this study would be convenient for government officials in developing more effective management policies and necessary steps to check and monitor the Ganga river water quality.It was also suggested that further investigations in terms of trace elemental sources and their role in self-purification properties of Ganga water can be addressed in future.
文摘In recent times the fixed point results in partially ordered metric spaces has greatly developed. In this paper we prove common fixed point results for multivalued and singlevalued mappings in partially ordered metric space. Our theorems generalized the theorem in [1] and extends the many more recent results in such spaces.
文摘The design details and performance characterization results of a newly developed plasma focus based compact and portable system(0.5 m×0.5 m×1.2 m,weighing≈100 kg)that produces an average neutron yield of^2×10^8 neutrons/shot(of fast D-D neutrons with typical energy^2.45 Me V)at^1.8 k J energy discharge are reported.From the detailed analysis of the experimental characterization and simulation results of this system,it has been conclusively revealed that specifically in plasma focus devices with larger static inductance:(i)pinch current is a reliable and more valid neutron yield scaling parameter than peak current,(ii)the ratio of pinch/peak current improves as static inductance of the system reduces,(iii)the benign role of the higher static/pinch inductance ratio enables the supply of inductively stored energy in densely pinched plasma with a larger time constant and it is well depicted by the extended dip observed in the discharge current trace,(iv)there is the need to redefine existing index values of the pinch(Ipinch^4.7)and peak(Ipeak^3.9)currents in neutron yield scaling equations to higher values.
文摘In view of the wide use of plants as test systems theeffects of acute and chronic exposure were comparedon seeds of Pisum sativum and in meristematic cellsof Allium sativum root tips.The two salts comparedwere zirconium oxychloride and known to be ubiquitousin plant systems and thallium acetate known for toxiceffects in high doses.Seeds were soaked in
文摘The effect of acute and chronic exposure to toxicmetals like CsCl and CoCl<sub>2</sub> on chromosomes and celldivision was studied in seeds of Trigonellafoenum graecum and root meristems of Alliumsativum.10,000,1000 & 100 ppm of CsCl and 1%,
文摘The action of metals on living organisms has to bestudied as mixtures since exposure is seldom to asingle metal.The interaction between metals mayaffect the degree of action on enzymes.
文摘Electromagnetic forming is a high-speed forming technology by which hollow profiles can be compressed or expanded. It is done with a pulsed magnetic field to apply Lorentz’ forces at electrically conductive material. Electromagnetic hollow tube expansion is limited by the fragmentation tendency. This work attempts to use a combination of analytical and computational approach to compute the net tangential stress during tube expansion. A simplified analytical framework to estimate the temporal evolution of plastic stresses present in aluminium alloy AA5052 at low and high applied magnetic pressures is developed based upon dynamic imaging. The time resolved images captured using current synchronised high speed camera record the overall dimensional changes of the tube that is validated by multi-physics simulation of expansion process. Imaging of hollow tube expansions at two selected peak currents has been carried out at various current levels in the range 76 - 160 kA. The direct visualisation of the increase in the tube diameter at two current levels provided a comparison of the developing net tangential stresses in the hollow tube during the undamaged and fragmented expansion. Imaging of tube expansion also facilitates the estimation of the strain rate experienced by the tube and was in the range of ~1700 s<sup>-1</sup> to ~1200 s<sup>-1</sup>. The propensity of fragmentation was found to be due to the level and duration of generated tangential stresses above the yield stress during expansion of the aluminium tubes. Presented study provides a mean of exploiting the enhanced formability of aluminium alloys using electromagnetic forming.
文摘The composite materials based on nanopowder dispersed liquid crystals are important both from fundamental research and device applications due to their unique properties such as improvement in various properties like electrical,optical,thermal,energy storage and spontaneous polarization etc.The proper selection of nanoparticle and its size which to be dispersed in particular liquid crystals is very important for a particular application.In the present study,a ferroelectric nanopowder of Barium Titanate(BaTiO3)was dispersed in cholesteric liquid crystal and the same was confirmed by Fourier Transform Infrared(FTIR)Spectroscopy.The various acoustical properties like ultrasonic velocity,density,Adiabatic Compressibility,Rao Constant,Wada Constant and Acoustic Impedance were investigated by ultrasonic interferometer at room temperature at fixed frequency.The dielectric constant was determined by Precision Impedance Analyzer.In addition to these investigations,particle size and surface area were also measured.Our investigation shows enhanced in dielectric and acoustical properties which may be useful for device applications extensively in microelectronics,low cost-photovoltaic devices,and custom-shaped containers possibly applied as a coating.
文摘The ubiquitous sameness of urban greenways prompts questions on generative design grammar and syntax, whether creative, critical rethinking at that level might be lacking. However the design syntax of urban greenways is not explicitly discussed thus leaving a critical gap in knowledge. This paper begins tackling the larger question by acting on the fundamental subset of it, by operationatizing the design syntax of urban greenways. This is done through mathematics-based graph studies to analyze patterns and shapes, photography based thermal, material and morphology studies, and section analyses to make imagery-derived deductions on the design syntax. Recommendation on approaches to diversify and enrich the design syntax includes a more direct reference from ecosystem science theories such for siting and planning the urban greenways at macro- to meso-scale, a mixed-method approach, combining mathe- matics, photography and drawings based frames for analyses at meso- to micro-scale, and a turtle view scale for designing at meso- to micro-scale, with an emphasis on latter.