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Interdisciplinary researches for potential developments of drugs and natural products
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作者 arunrat chaveerach Runglawan Sudmoon Tawatchai Tanee 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2017年第4期378-384,共7页
Developments of drugs or natural products from plants are possibly made, simple to use and lower cost than modern drugs.The development processes can be started with studying local wisdom and literature reviews to cho... Developments of drugs or natural products from plants are possibly made, simple to use and lower cost than modern drugs.The development processes can be started with studying local wisdom and literature reviews to choose the plants which have long been used in diverse areas, such as foods, traditional medicine, fragrances and seasonings.Then those data will be associated with scientific researches, namely plant collection and identification, phytochemical screening by gas chromatography-mass spectrometry,pharmacological study/review for their functions, and finally safety and efficiency tests in human.For safety testing, in vitro cell toxicity by cell viability assessment and in vitro testing of DNA breaks by the comet assay in human peripheral blood mononuclear cells can be performed.When active chemicals and functions containing plants were chosen with safety and efficacy for human uses, then, the potential medicinal natural products will be produced.Based on these procedures, the producing cost will be cheaper and the products can be evaluated for their clinical properties.Thus, the best and lowest-priced medicines and natural products can be distributed worldwide. 展开更多
关键词 Cell viability Comet assay Drug development GC–MS
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Two new species of Curcuma (Zingiberaceae) used as cobra-bite antidotes
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作者 arunrat chaveerach Runglawan SUDMOON +3 位作者 Tawatchai TANEE Piya MOKKAMUL Nison SATTAYASAI Jintana SATTAYASAI 《植物分类学报》 CSCD 北大核心 2008年第1期80-88,共9页
Two new species of Curcuma, C. sattayasaii A. Chaveerach & R. Sudmoon and C. zedoaroides A. Chaveerach & T. Tanee with rhizomes traditionally used for many decades as cobra-bite antidotes are described and illustrat... Two new species of Curcuma, C. sattayasaii A. Chaveerach & R. Sudmoon and C. zedoaroides A. Chaveerach & T. Tanee with rhizomes traditionally used for many decades as cobra-bite antidotes are described and illustrated. Curcuma sattayasaii is similar to C. longa L., but differs in rhizome horizontally branching on ground; coma bracts pinkish-white or pinkish-pale green; corolla pale yellow with orange tip; labellum pale orange with an orange central band; anther crest very short, broadly ovate, wider than long. Curcuma zedoaroides is similar to C. zedoaria (Christm.) Roscoe, but differs in rhizome branching pattern; the protruding secondary rhizomes curved down; blades oblong to oblong-lanceolate; peduncle glabrous; fertile and coma bracts glabrous; corolla lobes pale yellow to white, lateral lobe ovate, dorsal lobe broadly ovate. The new taxa have been found in a village of Khon Kaen Province, Northeastern Thailand. 展开更多
关键词 CURCUMA Curcuma sattayasaii A. Chaveerach R. Sudmoon Curcuma zedoaroides A. Chaveerach T. Tanee cobra-bite antidote new species Khon Kaen Thailand
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