Soft corals are well-known as excellent sources of marine-derived natural products.Among them,members of the genera Sar-cophyton,Sinularia,and Lobophytum are especially attractive targets for marine natural product re...Soft corals are well-known as excellent sources of marine-derived natural products.Among them,members of the genera Sar-cophyton,Sinularia,and Lobophytum are especially attractive targets for marine natural product research.In this review,we reported the marine-derived natural products called cembranoids isolated from soft corals,including the genera Sarcophyton,Sinularia,and Lobophytum.Here,we reviewed 72 reports published between 2016 and 2020,comprising 360 compounds,of which 260 are new compounds and 100 are previously known compounds with newly recognized activities.The novelty of the organic molecules and their relevant biological activities,delivered by the year of publication,are presented.Among the genera presented in this report,Sarcophyton spp.produce the most cembranoid diterpenes;thus,they are considered as the most important soft corals for marine natural product research.Cembranoids display diverse biological activities,includ-ing anti-cancer,anti-bacterial,and anti-inflammatory.As cembranoids have been credited with a broad range of biological activities,they present a huge potential for the development of various drugs with potential health and ecological benefits.展开更多
Rare sugars have attracted much attention since they are highly beneficial for health as alternative sweeteners and full of potential economic value in industry.The limited availability of rare sugars in nature has pr...Rare sugars have attracted much attention since they are highly beneficial for health as alternative sweeteners and full of potential economic value in industry.The limited availability of rare sugars in nature has promoted efforts on the conversion of sugars obtained from terrestrial plants into rare sugars,either via biological or chemo-catalytic approaches.However,the processes are generally complicated and consist of multiple steps.Macroalgae or seaweeds have been industrially used as a natural source of phycocolloids.These water-soluble polysaccharides contain monomeric sugars with unique chemical structures and are categorized as rare.In this review,the potency of macroalgae as a sustainable source of rare sugars and the recent progress on their catalytic conversion,either via biological or chemo-catalytical process,are summarized and discussed.Especially,the depolymerization of macroalgae for the production of rare sugars is presented.It is expected to enrich our knowledge in the development of sustainable production of rare sugars from macroalgae.展开更多
基金This research was funded by the Indonesian Institute of Sciences(LIPI)through the DIPA 2021 Research Fund B-10405/IPH/HK.01.03/XI/2020。
文摘Soft corals are well-known as excellent sources of marine-derived natural products.Among them,members of the genera Sar-cophyton,Sinularia,and Lobophytum are especially attractive targets for marine natural product research.In this review,we reported the marine-derived natural products called cembranoids isolated from soft corals,including the genera Sarcophyton,Sinularia,and Lobophytum.Here,we reviewed 72 reports published between 2016 and 2020,comprising 360 compounds,of which 260 are new compounds and 100 are previously known compounds with newly recognized activities.The novelty of the organic molecules and their relevant biological activities,delivered by the year of publication,are presented.Among the genera presented in this report,Sarcophyton spp.produce the most cembranoid diterpenes;thus,they are considered as the most important soft corals for marine natural product research.Cembranoids display diverse biological activities,includ-ing anti-cancer,anti-bacterial,and anti-inflammatory.As cembranoids have been credited with a broad range of biological activities,they present a huge potential for the development of various drugs with potential health and ecological benefits.
基金Indonesian Institute of Sciences(LIPI),Indonesia for Financial Support through National Priority Program“MALSAI”2021,registration number IPKLIPI-0014.
文摘Rare sugars have attracted much attention since they are highly beneficial for health as alternative sweeteners and full of potential economic value in industry.The limited availability of rare sugars in nature has promoted efforts on the conversion of sugars obtained from terrestrial plants into rare sugars,either via biological or chemo-catalytic approaches.However,the processes are generally complicated and consist of multiple steps.Macroalgae or seaweeds have been industrially used as a natural source of phycocolloids.These water-soluble polysaccharides contain monomeric sugars with unique chemical structures and are categorized as rare.In this review,the potency of macroalgae as a sustainable source of rare sugars and the recent progress on their catalytic conversion,either via biological or chemo-catalytical process,are summarized and discussed.Especially,the depolymerization of macroalgae for the production of rare sugars is presented.It is expected to enrich our knowledge in the development of sustainable production of rare sugars from macroalgae.
