Correlation between the Laboratory Test Results and Knee Functional Improvement of Pre- and Post-Total Knee Replacement Operation

Objective: This study aimed to identify correlations of laboratory test results and knee joint function between pre- and post-operation of knee joint replacement surgery. Methods: The study covered 60 - 75 aged 50 patients who had operated with knee replacement surgery. 25 patients were male and another 25 patients were female. We compared laboratory test results of pre- and 3rd, 7th and 14th day of post-operation. Moreover, pre-operation knee joint function was compared with 3rd, 7th, 14th and 30th day of post-operation. Furthermore, we investigated the relationship among WBC, hemoglobin and function tests. Pre- and post-operative knee joint function tests were conducted by WOMAC (The Western On-tario and McMaster Universities Osteoarthritis), VAS (Visual Analogue Scale), TUG (Time up and Go) score, and MMT (Muscle Manual Test). Results: In pre-operation, patients’ average WBC was 6.447 ± 2.115 cells/μL, monocyte was 6.554 ± 3.101 cells/μL, lymphocyte was 31.177 ± 9.512 cells/μL and C-reactive protein was 0.6205 ± 0.922 mg/dL. In 3rd day of post-operation, WBC was 8.901 ± 2.869 cells/μL, monocyte was 4.881 ± 2.332 cells/μL, lymphocyte was 17.048 ± 9.702 cells/μL and C-reactive protein was 4.2762 ± 2.293 mg/dL. There was a statistically significant difference reported on pre- and post-operation pain, stiffness and daily activity (P rd day of post-operation were raised up and they were statistically significant (P rd, 7th, 14th day of TUG score was significantly correlated (P Conclusion: Results of WBC, hemoglobin, hematocrit, total protein, total bilirubin, and creatinine had increased in 3rd and 7th day of post-operation and had stabilized from 14th day of post-operation. Stiffness and TUG performance were controversially correlated in 3rd, 7th, 14th, 30th day of post-operation. However, in 7th and 14th of post-operation, patients’ muscle strength and knee joint amplitude had become stabilized and improved from 30th day of post-operation. Moreover, after the operation, the number of WBC controversially affected patients’ mobility. In addition, we found that as hemoglobin and red blood cells increased, walking ability improved as well.

The Structure of Internal Blood Vessels in Mongolian Fetal Vertebral Bodies

Purpose: Investigate specific characteristic of blood supply of fetal vertebral bodies. Material & Methods: 16 - 30 week aged 20 fetuses (10 male, 10 female) were used for the study. Norms and requirements of Bio-Medical Ethics have not been violated in the use of human material in the study. Black-ink perfusion and cast of substance absorbing X-ray were applied in the fetuses. Results: Three concentric zones could be distinguished in the vascular architecture of the fetal vertebral bodies. 1) The peripheral zone of perichondrial vessels;2) The intermediate zone of radial vessels. 3. The central zone of the ossification centre vessels. We used black-ink perfusion and cast of substance absorbing X-ray were applied in the fetuses. Periosteum of fetal vertebral bodies are distributed originating from fine arteries of 70 - 120 diameter and arterioles of 30 - 50 diameter which are part of arteries of network of micro blood circulation. Venules are followed along two sides of this arteriole and short precapillaries are branched out in tree-like manner from it forming capillary network surrounding arteriole and capillary plexuses. Postcapillaries branched from the network are being emerged the venules accompanied arterioles. Conclusions: Micro blood circulatory system of the vertebrae has angion structure. The peripheral zone of perichondrial vessels has combined blood supply surrounded by blindly ending capillary network drained up and down from the central zone. The central zone of vertebral body is supplied with blood by the main arteriole.

Morphological Measurements of Knee Joints in Mongolian Population

Objective: This study was aimed to determine anthropometric measurements of knee joint among healthy Mongolian population and identify FML (Femur Medial Lateral), TML (Tibia Media Lateral), PML (Patella Medial Lateral), PAP (Patella Anterior Posterior), FAP (Femur Anterior Posterior) and TAP (Tibia Anterior Posterior). Methods: This cross-sectional study included 100 participants. We measured femoral, tibial and patellar dimensions using X-ray. Result: A total of 100 participants (44 male, 56 female participants) enrolled in this study. Age was ranged 20 - 59 and average age was 38 ± 9. Average FAP was 70.6 ± 1.22 mm in male and 66.9 ± 3.93 mm in female. Average TML in male was 85.6 ± 1.27 mm and 79.1 ± 0.8 mm in female. Average TAP was 60.1 ± 4.87 mm in male and 55.7 ± 4.96 in female. Average PAP was 22.5 ± 2.83 mm in male and 23.8 ± 2.43 mm in female. Average PML was 50.2 ± 1.45 mm in male and 46.8 ± 4.09 mm in female. Knee anthropometric measurements were statistically different in gender (P Conclusion: Participants average FML was statistically lower than Asian and European people and FAP was statistically higher than them.

Structural Changes in Vertebrae of Mice Based on Experimental Model of Rheumatoid Arthritis

Studies have shown that autoimmunity causes pathogenesis of more than 100 diseases. Among these diseases, approximately 1-2% of the world’s population has rheumatoid arthritis disease, which is a chronic disease that affects 45 out of every 3000 people who have autoimmune diseases. The aim of this research is to address the possible treatment of rheumatoid arthritis disease by comparing and contrasting the effectiveness and influence that treatments have on treating the disease. This study will be conducted by inducing the following treatments: ibuprofen and Boigor-10 on model animal subjects (mice) to determine the outcomes of the treatment. We will assess the outcomes by investigate the structural changes on vertebrae and joints of these subjects and the clinical manifestation score of each treatment. We hypothesize that these treatments will improve the treatment of rheumatoid arthritis disease. Furthermore, we hope that this research contributes to further understanding autoimmune disease and promotes proper treatment of the disease.