<b><span style="font-family:"">Background</span></b></span><span><span><b><span style="font-family:"">: </span></b></s...<b><span style="font-family:"">Background</span></b></span><span><span><b><span style="font-family:"">: </span></b></span></span><span><span><span style="font-family:"">Concomitant repair of moderate secondary tricuspid regurgitation (STR) during mitral valve surgery is still subject of <span>controverse</span>. </span></span></span><span><span><span style="font-family:"">This </span></span></span><span><span><span style="font-family:"">research </span></span></span><span><span><span style="font-family:"">aims to </span></span></span><span><span><span style="font-family:"">study</span></span></span><span><span><span style="font-family:""> the early </span></span></span><span><span><span style="font-family:"">and mid-term </span></span></span><span><span><span style="font-family:"">postoperative</span></span></span><span><span><span style="font-family:""> influence of tricuspid repair</span></span></span><span><span><span style="font-family:""> on </span></span></span><span><span><span style="font-family:"">the clinical outcomes and</span></span></span><span><span><span style="font-family:""> right ventric</span></span></span><span><span><span style="font-family:"">ular functions. </span></span></span><span><span><b><span style="font-family:"">Methods: </span></b></span></span><span><span><span style="font-family:"">This is a </span></span></span><span><span><span style="font-family:"">retrospective</span></span></span><span><span><span style="font-family:""> cohort study of </span></span></span><span><span><span style="font-family:"">92</span></span></span><span><span><span style="font-family:""> patients with </span></span></span><span><span><span style="font-family:"">moderate STR </span></span></span><span><span><span style="font-family:"">who</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">und<span>erwent tricuspid valve repair</span></span></span></span><span><span><span style="font-family:""> b</span></span></span><span><span><span style="font-family:"">etween </span></span></span><span><span><span style="font-family:"">October</span></span></span><span><span><span style="font-family:""> 20</span></span></span><span><span><span style="font-family:"">14</span></span></span><span><span><span style="font-family:""> and</span></span></span><span><span><span style="font-family:""> December</span></span></span><span><span><span style="font-family:""> 2</span></span></span><span><span><span style="font-family:"">017</span></span></span><span><span><span style="font-family:"">, in the cardiothoracic surgery department</span></span></span><span><span><span style="font-family:"">, Menoufia University Hospital</span></span></span><span><span><span style="font-family:"">. Patients were assessed clinically and by echocardiography </span></span></span><span><span><span style="font-family:"">at one month</span></span></span><span><span><span style="font-family:""> and after </span></span></span><span><span><span style="font-family:"">24 months postoperatively</span></span></span><span><span><span style="font-family:""> for the degree of tricuspid regurgitation</span></span></span><span><span><span style="font-family:""> (TR)</span></span></span><span><span><span style="font-family:"">,</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">right ventricular diameter <span>and</span> tricuspid annular plane systolic excursion (TAPSE)</span></span></span><span><span><span style="font-family:"">. </span></span></span><span><span><b><span style="font-family:"">Results:</span></b></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">In this study, <span>mean</span> a</span></span></span><span><span><span style="font-family:"">ge </span></span></span><span><span><span style="font-family:"">of patients was </span></span></span><span><span><span style="font-family:"">58.33 ± 4.06 years</span></span></span><span><span><span style="font-family:"">. We had a significant improvement in the grade of TR from <span>preoperative</span> period to <span>follow up</span> data observed at 1-month postoperative and 2-years <span>follow</span></span></span></span><span><span><span style="font-family:"">-</span></span></span><span><span><span style="font-family:"">up</span></span></span><span><span><span style="font-family:""> (P = 0.0001). After one month postoperatively, no TR was detected in 74 cases (80.4%), and in 71 (84.5%) after two years. Mean right ventricular diameter decr</span></span></span><span><span><span style="font-family:"">eased significantly from 23 ± 3.32 mm preoperatively to 21.9 ± 3 mm at 2-years postoperatively. An increase of TAPSE</span></span></span><span><span><span style="font-family:""> was</span></span></span><span><span><span style="font-family:""> from 19.96 ± 3.7 mm preoperatively to 20.3 ± 3.9 mm at 1-month postoperative (p = 0.55) and there was <span>significant</span> increase in late postoperative value. </span></span></span><span><span><b><span style="font-family:"">Conclusion:</span></b></span></span><span><span><b><span style="font-family:""> </span></b></span></span><span><span><span style="font-family:"">W</span></span></span><span><span><span style="font-family:"">e highly recommend repair for</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">moderate </span></span></span><span><span><span style="font-family:"">TR</span></span></span><span><span><span style="font-family:""> during mitral valve surgery</span></span></span><span><span><span style="font-family:""> t</span></span></span><span><span><span style="font-family:"">o avoid progression of </span></span></span><span><span><span style="font-family:"">TR</span></span></span><span><span><span style="font-family:"">. </span></span></span><span><span><span style="font-family:"">Tricuspid</span></span></span><span><span><span style="font-family:""> repair</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">was</span></span></span><span><span><span style="font-family:""> able to reduce the grade of </span></span></span><span><span><span style="font-family:"">regurgitation</span></span></span><span><span><span style="font-family:""> after </span></span></span><span><span><span style="font-family:"">two years of </span></span></span><span><span><span style="font-family:"">surgery and </span></span></span><span><span><span style="font-family:"">improved</span></span></span><span><span><span style="font-family:""> right ventricular functions.展开更多
文摘<b><span style="font-family:"">Background</span></b></span><span><span><b><span style="font-family:"">: </span></b></span></span><span><span><span style="font-family:"">Concomitant repair of moderate secondary tricuspid regurgitation (STR) during mitral valve surgery is still subject of <span>controverse</span>. </span></span></span><span><span><span style="font-family:"">This </span></span></span><span><span><span style="font-family:"">research </span></span></span><span><span><span style="font-family:"">aims to </span></span></span><span><span><span style="font-family:"">study</span></span></span><span><span><span style="font-family:""> the early </span></span></span><span><span><span style="font-family:"">and mid-term </span></span></span><span><span><span style="font-family:"">postoperative</span></span></span><span><span><span style="font-family:""> influence of tricuspid repair</span></span></span><span><span><span style="font-family:""> on </span></span></span><span><span><span style="font-family:"">the clinical outcomes and</span></span></span><span><span><span style="font-family:""> right ventric</span></span></span><span><span><span style="font-family:"">ular functions. </span></span></span><span><span><b><span style="font-family:"">Methods: </span></b></span></span><span><span><span style="font-family:"">This is a </span></span></span><span><span><span style="font-family:"">retrospective</span></span></span><span><span><span style="font-family:""> cohort study of </span></span></span><span><span><span style="font-family:"">92</span></span></span><span><span><span style="font-family:""> patients with </span></span></span><span><span><span style="font-family:"">moderate STR </span></span></span><span><span><span style="font-family:"">who</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">und<span>erwent tricuspid valve repair</span></span></span></span><span><span><span style="font-family:""> b</span></span></span><span><span><span style="font-family:"">etween </span></span></span><span><span><span style="font-family:"">October</span></span></span><span><span><span style="font-family:""> 20</span></span></span><span><span><span style="font-family:"">14</span></span></span><span><span><span style="font-family:""> and</span></span></span><span><span><span style="font-family:""> December</span></span></span><span><span><span style="font-family:""> 2</span></span></span><span><span><span style="font-family:"">017</span></span></span><span><span><span style="font-family:"">, in the cardiothoracic surgery department</span></span></span><span><span><span style="font-family:"">, Menoufia University Hospital</span></span></span><span><span><span style="font-family:"">. Patients were assessed clinically and by echocardiography </span></span></span><span><span><span style="font-family:"">at one month</span></span></span><span><span><span style="font-family:""> and after </span></span></span><span><span><span style="font-family:"">24 months postoperatively</span></span></span><span><span><span style="font-family:""> for the degree of tricuspid regurgitation</span></span></span><span><span><span style="font-family:""> (TR)</span></span></span><span><span><span style="font-family:"">,</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">right ventricular diameter <span>and</span> tricuspid annular plane systolic excursion (TAPSE)</span></span></span><span><span><span style="font-family:"">. </span></span></span><span><span><b><span style="font-family:"">Results:</span></b></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">In this study, <span>mean</span> a</span></span></span><span><span><span style="font-family:"">ge </span></span></span><span><span><span style="font-family:"">of patients was </span></span></span><span><span><span style="font-family:"">58.33 ± 4.06 years</span></span></span><span><span><span style="font-family:"">. We had a significant improvement in the grade of TR from <span>preoperative</span> period to <span>follow up</span> data observed at 1-month postoperative and 2-years <span>follow</span></span></span></span><span><span><span style="font-family:"">-</span></span></span><span><span><span style="font-family:"">up</span></span></span><span><span><span style="font-family:""> (P = 0.0001). After one month postoperatively, no TR was detected in 74 cases (80.4%), and in 71 (84.5%) after two years. Mean right ventricular diameter decr</span></span></span><span><span><span style="font-family:"">eased significantly from 23 ± 3.32 mm preoperatively to 21.9 ± 3 mm at 2-years postoperatively. An increase of TAPSE</span></span></span><span><span><span style="font-family:""> was</span></span></span><span><span><span style="font-family:""> from 19.96 ± 3.7 mm preoperatively to 20.3 ± 3.9 mm at 1-month postoperative (p = 0.55) and there was <span>significant</span> increase in late postoperative value. </span></span></span><span><span><b><span style="font-family:"">Conclusion:</span></b></span></span><span><span><b><span style="font-family:""> </span></b></span></span><span><span><span style="font-family:"">W</span></span></span><span><span><span style="font-family:"">e highly recommend repair for</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">moderate </span></span></span><span><span><span style="font-family:"">TR</span></span></span><span><span><span style="font-family:""> during mitral valve surgery</span></span></span><span><span><span style="font-family:""> t</span></span></span><span><span><span style="font-family:"">o avoid progression of </span></span></span><span><span><span style="font-family:"">TR</span></span></span><span><span><span style="font-family:"">. </span></span></span><span><span><span style="font-family:"">Tricuspid</span></span></span><span><span><span style="font-family:""> repair</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:"">was</span></span></span><span><span><span style="font-family:""> able to reduce the grade of </span></span></span><span><span><span style="font-family:"">regurgitation</span></span></span><span><span><span style="font-family:""> after </span></span></span><span><span><span style="font-family:"">two years of </span></span></span><span><span><span style="font-family:"">surgery and </span></span></span><span><span><span style="font-family:"">improved</span></span></span><span><span><span style="font-family:""> right ventricular functions.