Objective:To identify the early predictors of severe envenomation in the southern region of Tunisia.Methods:It was a retrospective monocentric study including consecutive patients admitted to the emergency department ...Objective:To identify the early predictors of severe envenomation in the southern region of Tunisia.Methods:It was a retrospective monocentric study including consecutive patients admitted to the emergency department for snakebite envenomation.Snakebite envenomation was defined by a history of snakebite.Predictors of severe envenomation were determined by univariate and multivariate analyses.Results:Our sample consisted of 109 patients aged 30(20-44)years with a 1.1:1 sex-ratio(56 males and 53 females).During the 24-hour surveillance period,25 patients developed severe envenomation(22.9%).The in-hospital mortality rate was 4.6%(n=5).The independent predictors of severe snakebite envenomation were leucocyte count over 11550/mm3(OR:18.7,95%CI:3.3-107.8),creatine kinase over 155 IU/L(OR:6.16,95%CI:1.1-35.6),and/or tourniquet before arrival to the ED(OR:32.14,95%CI:3.5-295.9).Conclusions:This study emphasizes the importance of early evaluation of snakebite envenomation.Further studies are required to approve a severity scale proper to snakebite envenomation in Tunisia.展开更多
文摘Objective:To identify the early predictors of severe envenomation in the southern region of Tunisia.Methods:It was a retrospective monocentric study including consecutive patients admitted to the emergency department for snakebite envenomation.Snakebite envenomation was defined by a history of snakebite.Predictors of severe envenomation were determined by univariate and multivariate analyses.Results:Our sample consisted of 109 patients aged 30(20-44)years with a 1.1:1 sex-ratio(56 males and 53 females).During the 24-hour surveillance period,25 patients developed severe envenomation(22.9%).The in-hospital mortality rate was 4.6%(n=5).The independent predictors of severe snakebite envenomation were leucocyte count over 11550/mm3(OR:18.7,95%CI:3.3-107.8),creatine kinase over 155 IU/L(OR:6.16,95%CI:1.1-35.6),and/or tourniquet before arrival to the ED(OR:32.14,95%CI:3.5-295.9).Conclusions:This study emphasizes the importance of early evaluation of snakebite envenomation.Further studies are required to approve a severity scale proper to snakebite envenomation in Tunisia.
