This report describes the clinical and pathological aspects of an apocrine sweat gland carcinoma with distant metastasis in an aged dog.A 7-year-old male terrier dog was referred to small animal hospital of Shuhid Bah...This report describes the clinical and pathological aspects of an apocrine sweat gland carcinoma with distant metastasis in an aged dog.A 7-year-old male terrier dog was referred to small animal hospital of Shuhid Bahonar University of Kerman with a 5.5×3.5 centimeter pedunculated mass on its head near left auricular region which had been progressively growing since tliree months ago.The radiography showed no local and distant metastasis.Surgical excision and histological evaluation was done.Histologically,the mass was composed of epithelial cells arranged in glandular and solid patterns.The morphologic findings suggested either a primary or metastatic apocrine-gland carcinoma.Immunohistochemically,the tumor cells were intensely positive for cytokeratin 7 and 20 and negative for S100 protein.On the basis of histopathological and clinical findings,the tumor was diagnosed as a malignant apocrine gland tumor,arising from apocrine sweat glands of the skin.Local tumor recurrence with anorexia and weight loss was reported by the owner nine month later.Severe submandibular and prescapular lymphadenomegaly was noted in clinical examination.Several large pulmonary nodules were noted in chest radiographs resembling mediastinal lymph node metastasis.Second surgery and chemotherapy was rejected by the owner due to grave prognosis of the patient.The animal was died 45 days later due to respiratory complications.Tumors of apocrine sweat glands are relatively uncommon in dogs whereas apocrine gland adenocarcinoma with distant metastasis is extremely rare.展开更多
A five-year-old cow was referred to the veterinary faculty hospital for treatment of a swelling mass with a cutaneous fistula at the left lower part of the chest wall,between 7|h till 9th intercostals space.Abdominal ...A five-year-old cow was referred to the veterinary faculty hospital for treatment of a swelling mass with a cutaneous fistula at the left lower part of the chest wall,between 7|h till 9th intercostals space.Abdominal pain in palpation of the mass was observed with no abnormality in clinical symptoms.In surgical exploration,skin incision was carried out on the swelling mass and surprisingly a sinus tract with a sharp metallic rod(26 cm length)that continued to the reticulum lumen was identified.Because of unsuccessful attempting to remove of the foreign body,flank laparotomy and rumenotomy was performed.After one month,the cow led to complete recovery.展开更多
文摘This report describes the clinical and pathological aspects of an apocrine sweat gland carcinoma with distant metastasis in an aged dog.A 7-year-old male terrier dog was referred to small animal hospital of Shuhid Bahonar University of Kerman with a 5.5×3.5 centimeter pedunculated mass on its head near left auricular region which had been progressively growing since tliree months ago.The radiography showed no local and distant metastasis.Surgical excision and histological evaluation was done.Histologically,the mass was composed of epithelial cells arranged in glandular and solid patterns.The morphologic findings suggested either a primary or metastatic apocrine-gland carcinoma.Immunohistochemically,the tumor cells were intensely positive for cytokeratin 7 and 20 and negative for S100 protein.On the basis of histopathological and clinical findings,the tumor was diagnosed as a malignant apocrine gland tumor,arising from apocrine sweat glands of the skin.Local tumor recurrence with anorexia and weight loss was reported by the owner nine month later.Severe submandibular and prescapular lymphadenomegaly was noted in clinical examination.Several large pulmonary nodules were noted in chest radiographs resembling mediastinal lymph node metastasis.Second surgery and chemotherapy was rejected by the owner due to grave prognosis of the patient.The animal was died 45 days later due to respiratory complications.Tumors of apocrine sweat glands are relatively uncommon in dogs whereas apocrine gland adenocarcinoma with distant metastasis is extremely rare.
文摘A five-year-old cow was referred to the veterinary faculty hospital for treatment of a swelling mass with a cutaneous fistula at the left lower part of the chest wall,between 7|h till 9th intercostals space.Abdominal pain in palpation of the mass was observed with no abnormality in clinical symptoms.In surgical exploration,skin incision was carried out on the swelling mass and surprisingly a sinus tract with a sharp metallic rod(26 cm length)that continued to the reticulum lumen was identified.Because of unsuccessful attempting to remove of the foreign body,flank laparotomy and rumenotomy was performed.After one month,the cow led to complete recovery.
