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MICROENDOSCOPIC SPECTRAL IMAGING AS A TOOL FOR SMALL DUCTUAL DIAGNOSTICS:PRELIMINARY EXPERIENCE
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作者 A.DOUPLIK W.L.LEONG +4 位作者 A.M.EASSON S.DONE b.c.wilson A.SHAHMOON Z.ZALEVSKY 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2012年第3期64-70,共7页
A technical feasibility of autofluorescence ductoscopy in breast milk ducts as blood vessels phantoms has been assessed as successful.Malignant tumor can be clearly identified through the milk ducts.We also present th... A technical feasibility of autofluorescence ductoscopy in breast milk ducts as blood vessels phantoms has been assessed as successful.Malignant tumor can be clearly identified through the milk ducts.We also present the operation principle as well as the preliminary experimental results of a new type of microsize multicorefiber that enables imaging through blood vessel phantoms.Imaging of a manipulated microwire through a drilled phantom is presented. 展开更多
关键词 Cancer margin delineation ENDOSCOPY MICROENDOSCOPY autofluorescence imaging surgical guidance multicorefibers
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光动力学疗法的单态氧剂量评估 被引量:4
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作者 李步洪 M.T.JARVI +1 位作者 E.H.MORIYAMA b.c.wilson 《中国科学(G辑)》 CSCD 2007年第B10期153-160,共8页
光动力学疗法(Photodynamic Therapy,PDT)是一种治疗肿瘤等疾病的一种新疗法.简要介绍了用于PDT剂量学研究的主要方法,重点阐述了利用单态氧(1O2)在1270nm的近红外发光进行PDT疗效评估的优点.利用新型光电倍增管和时间分辨光谱技术开发... 光动力学疗法(Photodynamic Therapy,PDT)是一种治疗肿瘤等疾病的一种新疗法.简要介绍了用于PDT剂量学研究的主要方法,重点阐述了利用单态氧(1O2)在1270nm的近红外发光进行PDT疗效评估的优点.利用新型光电倍增管和时间分辨光谱技术开发了一个用于PDT剂量评估的高灵敏度1O2发光检测系统.实验测量了玫瑰红的近红外发光光谱,三重态玫瑰红和1O2在水溶液中的寿命分别为(2.77±0.17)和(3.15±0.14)μs,结果表明所开发的1O2发光检测系统具有很高的灵敏度和测量精度.离体细胞实验结果进一步表明:细胞的存活率与PDT治疗过程中所产生的累积1O2发光光子数呈正相关,所开发的1O2发光检测系统适用于PDT剂量学研究. 展开更多
关键词 光动力学疗法 剂量 单态氧发光 细胞存活率 PpIX
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