石化工业气体致突变危险性评价——1.封闭式全玻璃气体器暴露装置的构建及啮齿类乙烯呼吸药理动力学研究

迄今为止,环境毒理学所研究的以哺乳动物为目标的有毒化合物大多局限于经由消化道或皮肤接触而被摄入体内的化学品,然而包括石化工业小分子量产物在内的许多环境化合物却主要是经由呼吸道,即通过呼吸作用进入人体的。与其它途径相比,由吸入(Inhalation)开始的毒理学过程在许多方面都有其特殊性。

ASSESSMENT OF MUTAGENIC RISK OF SOME PETROCHEMICAL GASES——Ⅰ.CONSTRUCTION OF A CLOSED ALL-GLASS GAS EXPOSURE SYSTEM AND STUDY ON THE ETHYLENE INHALATION KINETICS OF RODENTS

Many environmental chemicals,including some smallmolecule petrochemical products are taken up by animalbody via,namely,respiratory tract,i.e.by the processof inhalation.