首先以吡喃型D-甘露糖为原料,合成糖单体2-(2,3,4,6-四-O-乙酰-α-D-吡喃甘露糖)甲基丙烯酸乙酯,并通过可逆加成断裂链转移(RAFT)聚合法制备了含双硫酯片段的聚2-(2,3,4,6-四-O-乙酰-α-D-吡喃甘露糖)甲基丙烯酸乙酯(PAc Man EMA);再以P...首先以吡喃型D-甘露糖为原料,合成糖单体2-(2,3,4,6-四-O-乙酰-α-D-吡喃甘露糖)甲基丙烯酸乙酯,并通过可逆加成断裂链转移(RAFT)聚合法制备了含双硫酯片段的聚2-(2,3,4,6-四-O-乙酰-α-D-吡喃甘露糖)甲基丙烯酸乙酯(PAc Man EMA);再以PAc Man EMA和1,2-二苯基-1,2-二[4'-(2″,3″-环氧丙氧基)苯基]乙烯(TPE-2DGE)为原料,通过"一锅法"得到结构规整的A-B-A型聚糖(PAc Man EMA-TPE);最后脱去乙酰化保护得到水溶性荧光聚糖(PMan EMA-TPE),产率为90%.通过核磁共振谱、傅里叶红外光谱、凝胶渗透色谱、荧光光谱以及细胞毒性实验等表征手段对所制备的聚合物进行结构、性能以及生物毒性研究.实验结果表明,目标荧光聚糖PAc Man EMA-TPE和PMan EMA-TPE均表现出明显的聚集诱导发光效应,且PMan EMA-TPE表现出较低毒性或者无毒性,具有作为生物医学探针的潜能.展开更多
The health conditions of highway bridges is critical for sustained transportation operations.US federal government mandates that all bridges built with public funds are to be inspected visually every two years. There ...The health conditions of highway bridges is critical for sustained transportation operations.US federal government mandates that all bridges built with public funds are to be inspected visually every two years. There is a growing consensus that additional rapid and non-intrusive methods for bridge damage evaluation are needed.This paper explores the potential of applying ground-based laser scanners for bridge damage evaluation. LiDAR has the potential of providing high-density,full-field surface static imaging.Hence,it can generate volumetric quantification of concrete corrosion or steel erosion.By recording object surface topology,LiDAR can detect different damages on the bridge structure and differentiate damage types according to the surface flatness and smoothness.To determine the effectiveness of LiDAR damage detection,two damage detection algorithms are presented and compared using scans on actual bridge damages.The results demonstrate and validate LiDAR damage quantification,which can be a powerful tool for bridge condition evaluation.展开更多
文摘首先以吡喃型D-甘露糖为原料,合成糖单体2-(2,3,4,6-四-O-乙酰-α-D-吡喃甘露糖)甲基丙烯酸乙酯,并通过可逆加成断裂链转移(RAFT)聚合法制备了含双硫酯片段的聚2-(2,3,4,6-四-O-乙酰-α-D-吡喃甘露糖)甲基丙烯酸乙酯(PAc Man EMA);再以PAc Man EMA和1,2-二苯基-1,2-二[4'-(2″,3″-环氧丙氧基)苯基]乙烯(TPE-2DGE)为原料,通过"一锅法"得到结构规整的A-B-A型聚糖(PAc Man EMA-TPE);最后脱去乙酰化保护得到水溶性荧光聚糖(PMan EMA-TPE),产率为90%.通过核磁共振谱、傅里叶红外光谱、凝胶渗透色谱、荧光光谱以及细胞毒性实验等表征手段对所制备的聚合物进行结构、性能以及生物毒性研究.实验结果表明,目标荧光聚糖PAc Man EMA-TPE和PMan EMA-TPE均表现出明显的聚集诱导发光效应,且PMan EMA-TPE表现出较低毒性或者无毒性,具有作为生物医学探针的潜能.
基金supported by grant number DTOS59-07-H-0005 from the United States Department of Transportation(USDOT), Research and Innovative Technology Administration (RITA)
文摘The health conditions of highway bridges is critical for sustained transportation operations.US federal government mandates that all bridges built with public funds are to be inspected visually every two years. There is a growing consensus that additional rapid and non-intrusive methods for bridge damage evaluation are needed.This paper explores the potential of applying ground-based laser scanners for bridge damage evaluation. LiDAR has the potential of providing high-density,full-field surface static imaging.Hence,it can generate volumetric quantification of concrete corrosion or steel erosion.By recording object surface topology,LiDAR can detect different damages on the bridge structure and differentiate damage types according to the surface flatness and smoothness.To determine the effectiveness of LiDAR damage detection,two damage detection algorithms are presented and compared using scans on actual bridge damages.The results demonstrate and validate LiDAR damage quantification,which can be a powerful tool for bridge condition evaluation.
