Objective This prospective single-arm clinical trial aimed to evaluated the feasibility and safety of the application of the SHURUI system(Beijing Surgerii Technology Co.,Ltd.,Beijing,China),a novel purpose-built robo...Objective This prospective single-arm clinical trial aimed to evaluated the feasibility and safety of the application of the SHURUI system(Beijing Surgerii Technology Co.,Ltd.,Beijing,China),a novel purpose-built robotic system,in single-port robotic radical prostatectomy.Methods Sixteen patients diagnosed with prostate cancer were prospectively enrolled in and underwent robotic radical prostatectomy from October 2021 to August 2022 by the SHURUI single-port robotic surgical system.The demographic and baseline data,surgical,oncological,and functional outcomes as well as follow-up data were recorded.Results The mean operative time was 226.3(standard deviation[SD]52.0)min,and the mean console time was 183.4(SD 48.3)min,with the mean estimated blood loss of 116.3(SD 90.0)mL.The mean length of postoperative hospital stay was 4.50(SD 0.97)days.Two patients had postoperative complications(Clavien-Dindo Grade II),and both patients improved after conservative treatment.All patients’postoperative prostate-specific antigen levels decreased to below 0.2 ng/mL 1 month after discharge.The mean prostate-specific antigen level further decreased to a mean of 0.0219(SD 0.0641)ng/mL 6 months after surgery.Thirty days postoperatively,12 out of 16 patients reported using no more than one urinary pad per day,and all patients reported satisfactory urinary control without the need for pads 6 months after surgery.Conclusion The SHURUI system is safe and feasible in performing radical prostatectomy via both transperitoneal and extraperitoneal approaches.Tumor control and urinary continence were satisfying for patients enrolled in.The next phase involves conducting a large-scale,multicenter randomized controlled trial to thoroughly assess the effectiveness and safety of the new technology in a broader population.展开更多
In this work,the (1-x)Bi_(0.5)Na_(0.5)TiO_(3)-xBaNi_(0.5)Nb_(0.5)O_(3)(BNT-BNN;0.00≤x≤ 0.20)ceramics were prepared via a high-temperature solid-state method.The crystalline structures,photovoltaic effect,and electri...In this work,the (1-x)Bi_(0.5)Na_(0.5)TiO_(3)-xBaNi_(0.5)Nb_(0.5)O_(3)(BNT-BNN;0.00≤x≤ 0.20)ceramics were prepared via a high-temperature solid-state method.The crystalline structures,photovoltaic effect,and electrical properties of the ceramics were investigated.According to X-ray diffraction,the system shows a single perovskite structure.The samples show the normal ferroelectric loops.With the increase of BNN content,the remnant polarization(P_(r))and coercive field(E_(c))decrease gradually.The optical band gap of the samples narrows from 3.10 to 2.27 eV.The conductive species of grains and grain boundaries in the ceramics are ascribed to the double ionized oxygen vacancies.The open-circuit voltage(V_(∝))of ~15.7 V and short-circuit current(J_(sc))of ~1450 nA/cm^(2) are obtained in the 0.95BNT-0.05BNN ceramic under 1 sun illumination(AM1.5G,100 mW/cm^(2)).A larger V_(∝) of 23 V and a higher J_(sc) of 5500 nA/cm^(2) are achieved at the poling field of 60 kV/cm under the same light conditions.The study shows this system has great application prospects in the photovoltaic field.展开更多
Oxygen-containing defects are very important for altering the nonlinear optical (NLO) properties of graphene. To investigate the correlation between oxygen-containing defects and the synergistic NLO response in graphe...Oxygen-containing defects are very important for altering the nonlinear optical (NLO) properties of graphene. To investigate the correlation between oxygen-containing defects and the synergistic NLO response in graphenebased nanocomposites, we attached CdS nanocrystals on the surface of graphene (G) and prepared G/CdS nanohybrids (NHs) consisting of various oxygen-containing functional groups via a chemical method. The NLO absorption and refraction of G/CdS NHs under single pulse laser irradiation are enhanced by 10.8 times with the concentration decrease of surface oxygen-containing groups, which might be attributed to the local field effects and synergetic effects stemming from charge transfer between the two components. However, the optical nonlinearity is decreased with further concentration decrease, which might arise from sp^2 fragment interconnection and surface defects in the NHs. The NLO absorption transformation from two-photon absorption to saturable absorption with oxygen decrease is observed, and intensity-related NLO absorption and refraction in NHs are also discussed. Meanwhile, the G/CdS NHs exhibit superior NLO properties, implying potential applications of NH material in NLO devices.展开更多
基金The authors would like to express their gratitude to Prof.Kai Xu and his research and development team from Shanghai Jiao Tong University,Shanghai,China,for their invaluable technical support of this study.This research was funded by the National Key Research and Development Program of China(Grant No.2022YFB4700904 to Wang L)Research-Oriented Physicians'Innovative Transformation Training Program of Development Center,Shanghai Shenkang Hospital,Shanghai,China(Grant No.SHDC2022CRS010B to Tang S).
文摘Objective This prospective single-arm clinical trial aimed to evaluated the feasibility and safety of the application of the SHURUI system(Beijing Surgerii Technology Co.,Ltd.,Beijing,China),a novel purpose-built robotic system,in single-port robotic radical prostatectomy.Methods Sixteen patients diagnosed with prostate cancer were prospectively enrolled in and underwent robotic radical prostatectomy from October 2021 to August 2022 by the SHURUI single-port robotic surgical system.The demographic and baseline data,surgical,oncological,and functional outcomes as well as follow-up data were recorded.Results The mean operative time was 226.3(standard deviation[SD]52.0)min,and the mean console time was 183.4(SD 48.3)min,with the mean estimated blood loss of 116.3(SD 90.0)mL.The mean length of postoperative hospital stay was 4.50(SD 0.97)days.Two patients had postoperative complications(Clavien-Dindo Grade II),and both patients improved after conservative treatment.All patients’postoperative prostate-specific antigen levels decreased to below 0.2 ng/mL 1 month after discharge.The mean prostate-specific antigen level further decreased to a mean of 0.0219(SD 0.0641)ng/mL 6 months after surgery.Thirty days postoperatively,12 out of 16 patients reported using no more than one urinary pad per day,and all patients reported satisfactory urinary control without the need for pads 6 months after surgery.Conclusion The SHURUI system is safe and feasible in performing radical prostatectomy via both transperitoneal and extraperitoneal approaches.Tumor control and urinary continence were satisfying for patients enrolled in.The next phase involves conducting a large-scale,multicenter randomized controlled trial to thoroughly assess the effectiveness and safety of the new technology in a broader population.
基金financially supported by the National Natural Science Foundation of China(Grant No.11464006)Guangxi Key Laboratory of Information Materials(Grant No.191026-Z).
文摘In this work,the (1-x)Bi_(0.5)Na_(0.5)TiO_(3)-xBaNi_(0.5)Nb_(0.5)O_(3)(BNT-BNN;0.00≤x≤ 0.20)ceramics were prepared via a high-temperature solid-state method.The crystalline structures,photovoltaic effect,and electrical properties of the ceramics were investigated.According to X-ray diffraction,the system shows a single perovskite structure.The samples show the normal ferroelectric loops.With the increase of BNN content,the remnant polarization(P_(r))and coercive field(E_(c))decrease gradually.The optical band gap of the samples narrows from 3.10 to 2.27 eV.The conductive species of grains and grain boundaries in the ceramics are ascribed to the double ionized oxygen vacancies.The open-circuit voltage(V_(∝))of ~15.7 V and short-circuit current(J_(sc))of ~1450 nA/cm^(2) are obtained in the 0.95BNT-0.05BNN ceramic under 1 sun illumination(AM1.5G,100 mW/cm^(2)).A larger V_(∝) of 23 V and a higher J_(sc) of 5500 nA/cm^(2) are achieved at the poling field of 60 kV/cm under the same light conditions.The study shows this system has great application prospects in the photovoltaic field.
基金National Natural Science Foundation of China (NSFC) (61404045,U1404624,61875053)Natural ScienceFoundation of Henan Province (144300510018)Scientific Research Funds of Henan University (CX0000A40680)
文摘Oxygen-containing defects are very important for altering the nonlinear optical (NLO) properties of graphene. To investigate the correlation between oxygen-containing defects and the synergistic NLO response in graphenebased nanocomposites, we attached CdS nanocrystals on the surface of graphene (G) and prepared G/CdS nanohybrids (NHs) consisting of various oxygen-containing functional groups via a chemical method. The NLO absorption and refraction of G/CdS NHs under single pulse laser irradiation are enhanced by 10.8 times with the concentration decrease of surface oxygen-containing groups, which might be attributed to the local field effects and synergetic effects stemming from charge transfer between the two components. However, the optical nonlinearity is decreased with further concentration decrease, which might arise from sp^2 fragment interconnection and surface defects in the NHs. The NLO absorption transformation from two-photon absorption to saturable absorption with oxygen decrease is observed, and intensity-related NLO absorption and refraction in NHs are also discussed. Meanwhile, the G/CdS NHs exhibit superior NLO properties, implying potential applications of NH material in NLO devices.