期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
环状RNA在肺部疾病中的研究进展 被引量:3
1
作者 王晨 蒋勇 +4 位作者 朱邦晖 伍国胜 孙瑜 贲道锋 夏照帆 《第二军医大学学报》 CAS CSCD 北大核心 2019年第8期885-888,共4页
肺部疾病是临床常见病,其发病率逐年升高且治疗难度日益增大,严重威胁人类的生命健康。高通量测序和基因芯片技术的长足发展使得被学术界忽略已久的环状RNA(circRNA)再度成为研究热点。CircRNA在生物体内均有广泛表达,对生物功能发挥着... 肺部疾病是临床常见病,其发病率逐年升高且治疗难度日益增大,严重威胁人类的生命健康。高通量测序和基因芯片技术的长足发展使得被学术界忽略已久的环状RNA(circRNA)再度成为研究热点。CircRNA在生物体内均有广泛表达,对生物功能发挥着重要的调控作用,并具有高度的特异性、稳定性和保守性,在疾病的诊疗方面潜力巨大。本文总结了circRNA在肺部疾病中的研究进展,为肺部疾病的诊治提供一定的理论依据。 展开更多
关键词 环状RNA 生物学标记 肺疾病 肺肿瘤
下载PDF
Unplanned decannulation of tracheotomy tube in massive burn patients: a retrospective case series study 被引量:2
2
作者 ben dao-feng LU Kai-yang +8 位作者 CHEN Xu-lin YU Xi-ya XI Hui-Jun CHANG Fei ZHU Shi-hui TANG Hong-tai LU Wei MA bing XIA Zhao-tan 《Chinese Medical Journal》 SCIE CAS CSCD 2011年第20期3309-3313,共5页
Background Unplanned extubation is associated with adverse outcomes in intensive care unit. The massive burn patient differs from other critically ill patients in many ways. However, little is known about the unplanne... Background Unplanned extubation is associated with adverse outcomes in intensive care unit. The massive burn patient differs from other critically ill patients in many ways. However, little is known about the unplanned decannulation (UD) in Burn Intensive Care Unit. This paper describes the special features of the circumstances and outcome of UD of tracheotomy tube in massive burn patients. Methods A case series study was performed between January 1999 and December 2008 and UD of tracheotomy tube was analyzed retrospectively. A total of 21 patients with 29 UD events were identified. Demographic data, diagnosis, intervention, UD events and outcome of UD patients were collected. Differences in proportions were compared using the chi-square (X2) or Fisher's exact test. Results Patients with UD were often burned with head and neck (67%) and combined with inhalation injury (62%). The majority of them (76%) were transferred patients, occurred early (55%) and were accidental UD (79%). UD events tended to happen in day shift (90%) and to be associated with the medical procedure that was performing by caregivers at besides (79%). Loose of the stabilizing rope, medical procedure and tracheotomy malposition were the main causes of UD. Early UD and reintubation failure were associated with patients' death. Conclusions UD happened to massive burn patients can lead to patient death. Careful management of respiratory tract was essential for massive burn patients. 展开更多
关键词 unplanned decannulation airway management inhalation injury INTUBATION mechanical ventilation
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部