目的运用Meta分析方法研究加减射干麻黄汤治疗儿童咳嗽变异性哮喘的疗效及安全性。方法全面检索已发表中药射干麻黄汤为基础方或联合西药治疗儿童咳嗽变异性哮喘中干预措施为使用该方的临床随机对照试验的相关文献。两名评价人员分别进...目的运用Meta分析方法研究加减射干麻黄汤治疗儿童咳嗽变异性哮喘的疗效及安全性。方法全面检索已发表中药射干麻黄汤为基础方或联合西药治疗儿童咳嗽变异性哮喘中干预措施为使用该方的临床随机对照试验的相关文献。两名评价人员分别进行文献检索,用改良的Jadad量表进行文献质量评价、筛选出符合纳入条件的文献后对数据进行提取,最后采用Rev Man 5.3软件进行Meta分析。结果筛选并纳入13个随机对照试验,共1491例患者,经Meta分析显示,观察组有效率优于对照组,差异有统计学意义[RR=1.23,95%CI=(1.18,1.29),z=9.23,P<0.00001];咳嗽症状缓解时间短于对照组,差异有统计学意义[MD=-0.85,95%CI=(-0.94,-0.77),z=19.59,P<0.00001];不良反应发生率低于对照组,差异有统计学意义[RR=0.40,95%CI=(0.27,0.60),z=4.42,P<0.00001]。结论加减射干麻黄汤治疗儿童咳嗽变异性哮喘具有良好的疗效及安全性。展开更多
The Third International Conference on Space Information Technology (ICSIT) was held on November 27 in Beijing.The conference was hosted by China Academy of Space Technology (CAST) and organized by Space Star Technolog...The Third International Conference on Space Information Technology (ICSIT) was held on November 27 in Beijing.The conference was hosted by China Academy of Space Technology (CAST) and organized by Space Star Technology Co.,Ltd.,展开更多
A red pigment that has better biological properties is produced by marine bacterium strainS- 9801. The extraction methods, physicochemical and toxicity of the pigment have been studied. Dissolubility of pigment in the...A red pigment that has better biological properties is produced by marine bacterium strainS- 9801. The extraction methods, physicochemical and toxicity of the pigment have been studied. Dissolubility of pigment in the five organic solvent has been tested, and ethanol is optimally chosen for extraction. Physicochemical characteristics of this pigment was stable. The absorbance of the pigment solution was no losing when put under natural light for 10 days or treated by UV for 30 minutes, color of the pigment unchanged after 100℃ hythere for 1 h or 80 ℃ xerother for 2 h. The median lethal dose (LD_50) of the rat by celiac injection was 670.04 mg/kg and minimum lethal dose of oral was greater than 2 000 mg/kg.展开更多
SNARE proteins are a group of membrane-associated proteins involved in exocytosis, secretion and membrane trafficking events in eukaryotic cells. Research on SNARE protein biology has become a more attractive field in...SNARE proteins are a group of membrane-associated proteins involved in exocytosis, secretion and membrane trafficking events in eukaryotic cells. Research on SNARE protein biology has become a more attractive field in recent years, which is applied to marine biology specifically to the fish Tilapia (Oreochromis niloticus). Plasma membrane fractions of different tissues of Tilapia, including brain, liver-pancreas, intestine, skin and muscle, were extracted, and immuno-decorated with isoform-specific antibodies to the SNARE families and associated proteins. The presence of Syntaxins - 1 A, 2 and 3, SNAP - 23 and SNAP - 25, VAMP - 2, Munc - 18 - 1 and Munc - 13 in the brain was identified, which were differentially distributed in the other organ tissues of the fish Tilapia. The distinct distribution of SNARE and associated proteins will serve as the basis for further investigation into their special secretory function in these tissues of the fish.展开更多
In the early 1960s,with the ad-vent of the space era,it was quick-ly recognized that any object inspace was at risk due to the naturalmeteoroid environment.In the late1960s,it was recognized that
The in-orbit delivery ceremony of the FY-3C satellite,a polar orbiting meteorological satellite,was held in Beijing on May 5.The satellite was delivered to the China Meteorological Administration(CMA)by CASC officiall...The in-orbit delivery ceremony of the FY-3C satellite,a polar orbiting meteorological satellite,was held in Beijing on May 5.The satellite was delivered to the China Meteorological Administration(CMA)by CASC officially,marking the first operational satellite in the second generation of polar orbiting meteorological satellites of the country is capable of operational running and the transfer from展开更多
On October 5 of Venezuelan local time,witnessed by Venezuelan President Nicolas Maduro,President Yin Liming of China Great Wall Industry Corporation(CGWIC)and Minister Manuel Fernandes of Venezuelan Ministry of Higher...On October 5 of Venezuelan local time,witnessed by Venezuelan President Nicolas Maduro,President Yin Liming of China Great Wall Industry Corporation(CGWIC)and Minister Manuel Fernandes of Venezuelan Ministry of Higher Education,Science and Technology signed the contract for the Venezuelan Remote展开更多
Recently,Space Star Technology Co.,Ltd,CAST signed a contract on the Belorussian satellite’s ground application system with a Belorussian customer in Beijing,marking the formal implementation of the project.The custo...Recently,Space Star Technology Co.,Ltd,CAST signed a contract on the Belorussian satellite’s ground application system with a Belorussian customer in Beijing,marking the formal implementation of the project.The customer is a state-owned traditional hi-tech enterprise of Belarus,who brings forward extremely high展开更多
文摘目的运用Meta分析方法研究加减射干麻黄汤治疗儿童咳嗽变异性哮喘的疗效及安全性。方法全面检索已发表中药射干麻黄汤为基础方或联合西药治疗儿童咳嗽变异性哮喘中干预措施为使用该方的临床随机对照试验的相关文献。两名评价人员分别进行文献检索,用改良的Jadad量表进行文献质量评价、筛选出符合纳入条件的文献后对数据进行提取,最后采用Rev Man 5.3软件进行Meta分析。结果筛选并纳入13个随机对照试验,共1491例患者,经Meta分析显示,观察组有效率优于对照组,差异有统计学意义[RR=1.23,95%CI=(1.18,1.29),z=9.23,P<0.00001];咳嗽症状缓解时间短于对照组,差异有统计学意义[MD=-0.85,95%CI=(-0.94,-0.77),z=19.59,P<0.00001];不良反应发生率低于对照组,差异有统计学意义[RR=0.40,95%CI=(0.27,0.60),z=4.42,P<0.00001]。结论加减射干麻黄汤治疗儿童咳嗽变异性哮喘具有良好的疗效及安全性。
文摘The Third International Conference on Space Information Technology (ICSIT) was held on November 27 in Beijing.The conference was hosted by China Academy of Space Technology (CAST) and organized by Space Star Technology Co.,Ltd.,
文摘A red pigment that has better biological properties is produced by marine bacterium strainS- 9801. The extraction methods, physicochemical and toxicity of the pigment have been studied. Dissolubility of pigment in the five organic solvent has been tested, and ethanol is optimally chosen for extraction. Physicochemical characteristics of this pigment was stable. The absorbance of the pigment solution was no losing when put under natural light for 10 days or treated by UV for 30 minutes, color of the pigment unchanged after 100℃ hythere for 1 h or 80 ℃ xerother for 2 h. The median lethal dose (LD_50) of the rat by celiac injection was 670.04 mg/kg and minimum lethal dose of oral was greater than 2 000 mg/kg.
基金This work was funded by the State"863"Tech Program of China under contract High No.2002AA629120the National Natural Science Foundation of China under contract No.40476060the Canadian Institute for Health Research under contract No.M0P-64465.
文摘SNARE proteins are a group of membrane-associated proteins involved in exocytosis, secretion and membrane trafficking events in eukaryotic cells. Research on SNARE protein biology has become a more attractive field in recent years, which is applied to marine biology specifically to the fish Tilapia (Oreochromis niloticus). Plasma membrane fractions of different tissues of Tilapia, including brain, liver-pancreas, intestine, skin and muscle, were extracted, and immuno-decorated with isoform-specific antibodies to the SNARE families and associated proteins. The presence of Syntaxins - 1 A, 2 and 3, SNAP - 23 and SNAP - 25, VAMP - 2, Munc - 18 - 1 and Munc - 13 in the brain was identified, which were differentially distributed in the other organ tissues of the fish Tilapia. The distinct distribution of SNARE and associated proteins will serve as the basis for further investigation into their special secretory function in these tissues of the fish.
文摘In the early 1960s,with the ad-vent of the space era,it was quick-ly recognized that any object inspace was at risk due to the naturalmeteoroid environment.In the late1960s,it was recognized that
文摘The in-orbit delivery ceremony of the FY-3C satellite,a polar orbiting meteorological satellite,was held in Beijing on May 5.The satellite was delivered to the China Meteorological Administration(CMA)by CASC officially,marking the first operational satellite in the second generation of polar orbiting meteorological satellites of the country is capable of operational running and the transfer from
文摘On October 5 of Venezuelan local time,witnessed by Venezuelan President Nicolas Maduro,President Yin Liming of China Great Wall Industry Corporation(CGWIC)and Minister Manuel Fernandes of Venezuelan Ministry of Higher Education,Science and Technology signed the contract for the Venezuelan Remote
文摘Recently,Space Star Technology Co.,Ltd,CAST signed a contract on the Belorussian satellite’s ground application system with a Belorussian customer in Beijing,marking the formal implementation of the project.The customer is a state-owned traditional hi-tech enterprise of Belarus,who brings forward extremely high