There is some evidence consistently linking the occurrence of de novo obsessive-compulsive disorder(OCD) with clozapine. This skin-picking disorder is also known as impulsive-compulsive disorder-unspecified which with...There is some evidence consistently linking the occurrence of de novo obsessive-compulsive disorder(OCD) with clozapine. This skin-picking disorder is also known as impulsive-compulsive disorder-unspecified which with an increasing convergence with OCD has been placed in the current Diagnostic and statistical manual of mental disorders-fifth edition by American Psychiatric Association(DSM-5), in the category of the obsessive-compulsive and related disorders. To the best of our knowledge, there is no literature relating antipsychotics like clozapine with the occurrence of skin-picking behaviour. In this article, we present a case in whom skin-picking behaviour emerged during the upward dose titration of clozapine and was successfully treated with escitalopram.展开更多
INTRODUCTION Hashimoto’s encephalopathy presents with high serum antithyroid antibody concentra-tions in association with an excellent response to immunosuppressant therapies such as corticosteroids.1 Females were fo...INTRODUCTION Hashimoto’s encephalopathy presents with high serum antithyroid antibody concentra-tions in association with an excellent response to immunosuppressant therapies such as corticosteroids.1 Females were four to five times more likely to be affected by this condi-tion,with a mean age of onset between 41 and 48 years2,though rare occasional paediatric presentations were also reported.展开更多
文摘There is some evidence consistently linking the occurrence of de novo obsessive-compulsive disorder(OCD) with clozapine. This skin-picking disorder is also known as impulsive-compulsive disorder-unspecified which with an increasing convergence with OCD has been placed in the current Diagnostic and statistical manual of mental disorders-fifth edition by American Psychiatric Association(DSM-5), in the category of the obsessive-compulsive and related disorders. To the best of our knowledge, there is no literature relating antipsychotics like clozapine with the occurrence of skin-picking behaviour. In this article, we present a case in whom skin-picking behaviour emerged during the upward dose titration of clozapine and was successfully treated with escitalopram.
文摘INTRODUCTION Hashimoto’s encephalopathy presents with high serum antithyroid antibody concentra-tions in association with an excellent response to immunosuppressant therapies such as corticosteroids.1 Females were four to five times more likely to be affected by this condi-tion,with a mean age of onset between 41 and 48 years2,though rare occasional paediatric presentations were also reported.
