The large yellow croaker(Larimichthys crocea)is one of the most economically valuable marine fsh in China and is a notable species in ecological studies owing to a serious collapse of wild germplasm in the past few de...The large yellow croaker(Larimichthys crocea)is one of the most economically valuable marine fsh in China and is a notable species in ecological studies owing to a serious collapse of wild germplasm in the past few decades.The stock division and species distribution,which have important implications for ecological protection,germplasm recovery,and fshery resource management,have been debated since the 1960s.However,it is still uncertain even how many stocks exist in this species.To address this,we evaluated the fne-scale genetic structure of large yellow croaker populations distributed along the eastern and southern Chinese coastline based on 7.64 million SNP markers.Compared with the widely accepted stock boundaries proposed in the 1960s,our results revealed that a climate-driven habitat change probably occurred between the Naozhou(Nanhai)Stock and the Ming-Yuedong(Mindong)Stock.The boundary between these two stocks might have shifted northwards from the Pearl River Estuary to the northern area of the Taiwan Strait,accompanied by highly asymmetric introgression.In addition,we found divergent landscapes of natural selection between the stocks inhabiting northern and southern areas.The northern population exhibited highly agminated signatures of strong natural selection in genes related to developmental processes,whereas moderate and interspersed selective signatures were detected in many immune-related genes in the southern populations.These fndings establish the stock status and genome-wide evolutionary landscapes of large yellow croaker,providing a basis for conservation,fsheries management and further evolutionary biology studies.展开更多
Acid-controlled,chemodivergent and redox-neutral annulations for the synthesis of isocoumarins and isoquinolinones have been realized via Rh(Ⅲ)-cataIyzed C—H activation.Diazo compounds act as a carbene precursor,and...Acid-controlled,chemodivergent and redox-neutral annulations for the synthesis of isocoumarins and isoquinolinones have been realized via Rh(Ⅲ)-cataIyzed C—H activation.Diazo compounds act as a carbene precursor,and coupling occurs in one-pot process,where adipic acid and trimethylacetic acid promote chemodivergent cyclizations.展开更多
1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot ...1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot with the advantages of high functional groups tolerance, being transition metal-free, and employing environmentally friendly oxidants such as I2 and IBX. nroviding, access to the desired 1,2,4-triazine products in excellent yields.展开更多
基金We acknowledge financial support from the National Key R&D Program of China(no.2022YFD2401002)the National Science Fund for Distinguished Young Scholars(no.32225049)+5 种基金the National Natural Science Foundation of China(no.U21A20264)the Special Foundation for Major Research Program of Fujian Province(no.2020NZ08003)the Major Special Funding for"Science and Technology Innovation 2025"in Ningbo(no.2021Z002)the Local Science and Technology Development Project Guide by The Central Government(no.2019L3032)the China Agriculture Research System(no.CARS-47)the Alliance of International Science Organizations(ANSO-CR-PP-2021-03).
文摘The large yellow croaker(Larimichthys crocea)is one of the most economically valuable marine fsh in China and is a notable species in ecological studies owing to a serious collapse of wild germplasm in the past few decades.The stock division and species distribution,which have important implications for ecological protection,germplasm recovery,and fshery resource management,have been debated since the 1960s.However,it is still uncertain even how many stocks exist in this species.To address this,we evaluated the fne-scale genetic structure of large yellow croaker populations distributed along the eastern and southern Chinese coastline based on 7.64 million SNP markers.Compared with the widely accepted stock boundaries proposed in the 1960s,our results revealed that a climate-driven habitat change probably occurred between the Naozhou(Nanhai)Stock and the Ming-Yuedong(Mindong)Stock.The boundary between these two stocks might have shifted northwards from the Pearl River Estuary to the northern area of the Taiwan Strait,accompanied by highly asymmetric introgression.In addition,we found divergent landscapes of natural selection between the stocks inhabiting northern and southern areas.The northern population exhibited highly agminated signatures of strong natural selection in genes related to developmental processes,whereas moderate and interspersed selective signatures were detected in many immune-related genes in the southern populations.These fndings establish the stock status and genome-wide evolutionary landscapes of large yellow croaker,providing a basis for conservation,fsheries management and further evolutionary biology studies.
文摘Acid-controlled,chemodivergent and redox-neutral annulations for the synthesis of isocoumarins and isoquinolinones have been realized via Rh(Ⅲ)-cataIyzed C—H activation.Diazo compounds act as a carbene precursor,and coupling occurs in one-pot process,where adipic acid and trimethylacetic acid promote chemodivergent cyclizations.
基金Acknowledgement We are sincerely grateful for sponsorship of this project by the National Natural Science Foundation of China (No. 21372102).
文摘1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot with the advantages of high functional groups tolerance, being transition metal-free, and employing environmentally friendly oxidants such as I2 and IBX. nroviding, access to the desired 1,2,4-triazine products in excellent yields.